Elevated anti-sulfatide antibodies in Guillain-Barre syndrome in T cell depleted at end-stage AIDS

被引：9

作者：

Souayah, Nizar ^{[1
]}

Mian, Nimer F. ^{[1
]}

Gu, Yajuan ^{[1
]}

Ilyas, Amjad A. ^{[1
]}

机构：

[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Neurol & Neurosci, Newark, NJ 07103 USA

来源：

JOURNAL OF NEUROIMMUNOLOGY | 2007年 / 188卷 / 1-2期

关键词：

AIDS; HIV; Guillain-Barre syndrome; antibody; sulfatide;

D O I：

10.1016/j.jneuroim.2007.05.020

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A 38-year-old man developed the Guillain-Barre' syndrome (GBS) associated with untreated end-stage AIDS and CD4+ lymphocyte count of 3 cells/mm (3). The patient had serum high titer anti-sulfatide antibodies and responded well to infusion of immunoglobulin. The data suggest that elevated levels of anti-sulfatide antibodies may play a role in the pathogenesis of GBS in this patient, although a direct neurotropic effect of HIV virus cannot be excluded. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：143 / 145

页数：3

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