Effects of cholinergic receptor agonists and antagonists on miniature stimulatory postsynaptic ionic currents in somatic muscle cells of Lumbricus terrestris

被引：2
|
作者：
Volkov, EM [1 ]
Nurullin, LF [1 ]
机构：
[1] Kazan VI Lenin State Univ, Kazan 420008, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2005年 / 139卷 / 03期
基金：
俄罗斯基础研究基金会;
关键词：
acetylcholine receptor; cholinolytics; cholinomimetics; muscle cells; Lumbricus terrestris;
D O I：
10.1007/s10517-005-0294-2
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Miniature stimulating postsynaptic currents of Lumbricus terrestris somatic muscle cells were recorded. Atropine, d-tubocurarin, alpha-bungarotoxin, carbacholine, and proserin did not modify the amplitude and temporal parameters of miniature stimulatory postsynaptic currents, while carbacholine and nicotine depolarized the muscle membrane. Presumably, Lumbricus terrestris muscle cells contain acetylcholine-sensitive channel-receptor complexes not belonging to classical nicotinic or muscarinic acetylcholine receptors.
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页码：360 / 362
页数：3
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