Allosteric Gating Determinants in the Transmembrane Domain of Pentameric Ligand-Gated Ion Channels

被引：0
|
作者：
Howard, Rebecca J. [1 ]
Zhuang, Yuxuan [1 ]
Heusser, Stephanie A. [2 ]
Bergh, Cathrine C. [3 ]
Rovsnik, Urska [1 ]
Orellana, Laura [1 ]
Lindahl, Erik [1 ,3 ]
机构：
[1] Stockholm Univ, Dept Biochem & Biophys, Stockholm, Sweden
[2] Univ Copenhagen, Dept Drug Design & Pharmacol, Copenhagen, Denmark
[3] KTH Royal Inst Tech, Appl Phys, Stockholm, Sweden
来源：
BIOPHYSICAL JOURNAL | 2020年 / 118卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
2856-Pos
引用
收藏
页码：584A / 584A
页数：1
相关论文
共 50 条
  • [41] String method solution of the gating pathways for a pentameric ligand-gated ion channel
    Lev, Bogdan
    Murail, Samuel
    Poitevin, Frederic
    Cromer, Brett A.
    Baaden, Marc
    Delarue, Marc
    Allen, Toby W.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (21) : E4158 - E4167
  • [42] Structural Basis for Ion Permeation Mechanism in Pentameric Ligand-Gated Ion Channels
    Sauguet, Ludovic
    Poitevin, Frederic
    Murail, Samuel
    Van Renterghem, Catherine
    Moraga-Cid, Gustavo
    Malherbe, Laurie
    Thompson, Andrew
    Corringer, Pierre-Jean
    Baaden, Marc
    Delarue, Marc
    [J]. BIOPHYSICAL JOURNAL, 2013, 104 (02) : 67A - 67A
  • [43] Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel
    Hu, Haidai
    Howard, Rebecca J.
    Bastolla, Ugo
    Lindahl, Erik
    Delarue, Marc
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (24) : 13437 - 13446
  • [44] Calculation of Cholesterol Binding Affinity for Pentameric Ligand-Gated Ion Channels
    Salari, Reza
    Henin, Jerome
    Brannigan, Grace
    [J]. BIOPHYSICAL JOURNAL, 2014, 106 (02) : 340A - 340A
  • [45] Molecular Modeling of Charge Selectivity in Pentameric Ligand-Gated Ion Channels
    Harpole, Tyler J.
    Grosman, Claudio
    [J]. BIOPHYSICAL JOURNAL, 2016, 110 (03) : 602A - 602A
  • [46] Extracellular Contributions to Alcohol Modulation of Pentameric Ligand-Gated Ion Channels
    Plante, Amber
    [J]. BIOPHYSICAL JOURNAL, 2014, 106 (02) : 545A - 545A
  • [47] Structural Basis For Alcohol Modulation of Pentameric Ligand-Gated Ion Channels
    Howard, Rebecca J.
    Murail, Samuel
    Ondricek, Kathryn E.
    Corringer, Pierre-Jean
    Lindahl, Erik
    Trudell, James R.
    Harris, R. Adron
    [J]. BIOPHYSICAL JOURNAL, 2012, 102 (03) : 411A - 411A
  • [48] STRUCTURAL BASIS FOR ALCOHOL MODULATION OF PENTAMERIC LIGAND-GATED ION CHANNELS
    Howard, R. J.
    Murail, S.
    Broemstrup, T.
    Heusser, S. A.
    Horani, S.
    Lee, U. S.
    Ondricek, K. E.
    Corringer, P-J.
    Lindahl, E.
    Trudell, J. R.
    Harris, R. A.
    [J]. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2012, 36 : 116A - 116A
  • [49] Interplay between Gating and Block of Ligand-Gated Ion Channels
    Phillips, Matthew B.
    Nigam, Aparna
    Johnson, Jon W.
    [J]. BRAIN SCIENCES, 2020, 10 (12) : 1 - 22
  • [50] Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels
    Koniuszewski, Filip
    Vogel, Florian D.
    Bampali, Konstantina
    Fabjan, Jure
    Seidel, Thomas
    Scholze, Petra
    Schmiedhofer, Philip B.
    Langer, Thierry
    Ernst, Margot
    [J]. FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 9
12345