METABOLISM 'Channeling' Hans Krebs

被引：7
|
作者：
Tullman-Ercek, Danielle [1 ]
机构：
[1] Univ Calif Berkeley, Dept Chem & Biomol Engn, Berkeley, CA 94720 USA
来源：
NATURE CHEMICAL BIOLOGY | 2015年 / 11卷 / 03期
关键词：
D O I：
10.1038/nchembio.1758
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The physical arrangement of enzymes within native metabolic pathways is emerging as an important but underexplored area of molecular biology. Recent advances in mass spectrometry enabled confirmation of the proposal that the Krebs cycle enzymes form a complex and suggest that substrate channeling is the most likely benefit to this structural arrangement.
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页码：180 / 181
页数：3
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