IN CHRONIC LYMPHOCYTIC LEUKAEMIA WITH COMPLEX KARYOTYPE, MAJOR STRUCTURAL ABNORMALITIES IDENTIFY A SUBSET OF PATIENTS WITH INFERIOR OUTCOME AND DISTINCT BIOLOGIC CHARACTERISTICS

被引：0
|
作者：
Cavallari, M.
Rigolin, G. M.
Saccenti, E.
Guardalben, E.
Formigaro, L.
Zagatti, B.
Visentin, A.
Mauro, F. R.
Lista, E.
Bassi, C.
Lupini, L.
Quaglia, F. M.
Urso, A.
Bardi, M. A.
Bonaldi, L.
Volta, E.
Tammiso, E.
Ilari, C.
Cafforio, L.
Melandri, A.
Cavazzini, F.
Negrini, M.
Semenzato, G.
Trentin, L.
Foa, R.
Cuneo, A.
机构：
[1] Univ Ferrara, AOU S Anna, Dipartimento Sci Med, Sez Ematol, Ferrara, Italy
[2] Univ Ferrara, Dipartimento Morfol Chirurg & Med Sperimentale, Ferrara, Italy
[3] Univ Ferrara, LTTA, Ferrara, Italy
[4] Univ Padua, Dipartimento Med, Div Ematol, Padua, Italy
[5] Univ Sapienza, Dipartimento Sci Biomed & Ematol, Ematol, Rome, Italy
[6] IRCCS, Ist Oncol Veneto, Unita Immunol & Immunol Mol, Padua, Italy
来源：
HAEMATOLOGICA | 2018年 / 103卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
CO022
引用
收藏
页码：S28 / S29
页数：2
相关论文
共 20 条
  • [1] In chronic lymphocytic leukaemia with complex karyotype, major structural abnormalities identify a subset of patients with inferior outcome and distinct biological characteristics
    Rigolin, Gian Matteo
    Saccenti, Elena
    Guardalben, Emanuele
    Cavallari, Maurizio
    Formigaro, Luca
    Zagatti, Barbara
    Visentin, Andrea
    Mauro, Francesca R.
    Lista, Enrico
    Bassi, Cristian
    Lupini, Laura
    Quaglia, Francesca Maria
    Urso, Antonio
    Bardi, Maria Antonella
    Bonaldi, Laura
    Volta, Eleonora
    Tammiso, Elisa
    Ilari, Caterina
    Cafforio, Luciana
    Melandri, Aurora
    Cavazzini, Francesco
    Negrini, Massimo
    Semenzato, Gianpietro
    Trentin, Livio
    Foa, Robin
    Cuneo, Antonio
    BRITISH JOURNAL OF HAEMATOLOGY, 2018, 181 (02) : 229 - 233
  • [2] The landscape of genetic mutations in patients with chronic lymphocytic leukaemia and complex karyotype
    Strati, Paolo
    Wang, Feng
    Tambaro, Francesco P.
    Thompson, Philip A.
    Burger, Jan A.
    Jain, Nitin
    Ferrajoli, Alessandra
    Bose, Prithviraj
    Estrov, Zeev
    Keating, Michael J.
    Futreal, Andrew
    Takahashi, Koichi
    Wierda, William G.
    BRITISH JOURNAL OF HAEMATOLOGY, 2019, 187 (01) : E1 - E4
  • [3] Management strategies for patients with chronic lymphocytic leukaemia harbouring complex karyotype
    Serafin, Andrea
    Ruocco, Valeria
    Cellini, Alessandro
    Angotzi, Francesco
    Bonaldi, Laura
    Trentin, Livio
    Visentin, Andrea
    BRITISH JOURNAL OF HAEMATOLOGY, 2025, 206 (03) : 832 - 841
  • [4] Coexistence of light chain disease and chronic lymphocytic leukaemia, a complex karyotype with a rapid fatal outcome
    Castryck, H
    Van den Driessche, M
    Hagemeijer, A
    Stul, M
    Wynendaele, W
    Vandenberghe, P
    Moerman, J
    CLINICAL AND LABORATORY HAEMATOLOGY, 2006, 28 (02): : 138 - 140
  • [5] TP53 Abnormalities Are Underlying the Poor Outcome Associated with Chromothripsis in Chronic Lymphocytic Leukemia Patients with Complex Karyotype
    Ramos-Campoy, Silvia
    Puiggros, Anna
    Kamaso, Joanna
    Bea, Silvia
    Bougeon, Sandrine
    Jose Larrayoz, Maria
    Costa, Dolors
    Parker, Helen
    Rigolin, Gian Matteo
    Blanco, Maria Laura
    Collado, Rosa
    Ancin, Idoya
    Salgado, Rocio
    Moro-Garcia, Marco A.
    Baumann, Tycho
    Gimeno, Eva
    Moreno, Carol
    Salido, Marta
    Calvo, Xavier
    Jose Calasanz, Maria
    Cuneo, Antonio
    Nguyen-Khac, Florence
    Oscier, David
    Haferlach, Claudia
    Strefford, Jonathan C.
    Schoumans, Jacqueline
    Espinet, Blanca
    CANCERS, 2022, 14 (15)
  • [6] Complex karyotype predicts for inferior outcomes following reduced-intensity conditioning allogeneic transplant for chronic lymphocytic leukaemia
    Jaglowski, Samantha M.
    Ruppert, Amy S.
    Heerema, Nyla A.
    Bingman, Anissa
    Flynn, Joseph M.
    Grever, Michael R.
    Jones, Jeffrey A.
    Elder, Patrick
    Devine, Steven M.
    Byrd, John C.
    Andritsos, Leslie A.
    BRITISH JOURNAL OF HAEMATOLOGY, 2012, 159 (01) : 82 - 87
  • [7] Exploring the prognostic role of complex karyotype in chronic lymphocytic leukaemia patients treated with venetoclax-based regimens
    Serafin, Andrea
    Cellini, Alessandro
    Cavarretta, Chiara Adele
    Ruocco, Valeria
    Angotzi, Francesco
    Zatta, Ivan
    Frezzato, Federica
    Bonaldi, Laura
    Martines, Annalisa
    Pravato, Stefano
    Piazza, Francesco
    Trentin, Livio
    Visentin, Andrea
    BRITISH JOURNAL OF HAEMATOLOGY, 2024, 205 (01) : 189 - 193
  • [8] Additional lesions identified by genomic microarrays are associated with an inferior outcome in low-risk chronic lymphocytic leukaemia patients
    Rigolin, Gian Matteo
    Traversa, Alice
    Caputo, Viviana
    Del Giudice, Ilaria
    Bardi, Antonella
    Saccenti, Elena
    Raponi, Sara
    Ilari, Caterina
    Cafforio, Luciana
    Giovannetti, Agnese
    Pizzuti, Antonio
    Guarini, Anna
    Foa, Robin
    Cuneo, Antonio
    BRITISH JOURNAL OF HAEMATOLOGY, 2023, : 953 - 959
  • [9] Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome
    Martinez-Trillos, Alejandra
    Pinyol, Magda
    Navarro, Alba
    Aymerich, Marta
    Jares, Pedro
    Juan, Manel
    Rozman, Maria
    Colomer, Dolors
    Delgado, Julio
    Gine, Eva
    Gonzalez-Diaz, Marcos
    Hernandez-Rivas, Jesus M.
    Colado, Enrique
    Rayon, Consolacion
    Payer, Angel R.
    Jose Terol, Maria
    Navarro, Blanca
    Quesada, Victor
    Puente, Xose S.
    Rozman, Ciril
    Lopez-Otin, Carlos
    Campo, Elias
    Lopez-Guillermo, Armando
    Villamor, Neus
    BLOOD, 2014, 123 (24) : 3790 - 3796
  • [10] Outcome of Patients with Complex Karyotype in a Phase 3 Randomized Study of Idelalisib Plus Rituximab for Relapsed Chronic Lymphocytic Leukemia
    Kreuzer, Karl-Anton
    Furman, Richard R.
    Stilgenbauer, Stephan
    Dubowy, Ronald L.
    Kim, Yeonhee
    Munugalavadla, Veerendra
    Lilienweiss, Esther
    Reinhardt, Hans Christian
    Pettitt, Andrew R.
    Hallek, Michael
    BLOOD, 2016, 128 (22)
12