Augmented synthesis and secretion of leptin in obese spontaneously hypertensive rats (obese SHR) with a nonsense mutation of leptin receptor gene

被引:0
|
作者
Hiraoka, H
Ogawa, Y
Takaya, K
Hosoda, K
Ikeda, K
Nara, Y
Masuzaki, H
Sawamura, M
Koletsky, RJ
Yamori, Y
Nakao, K
机构
[1] N Coast Inst Diabet & Endocrinol, Westlake, OH 44145 USA
[2] Univ E Asia, Yamaguchi, Japan
[3] Kyoto Univ, Kyoto 606, Japan
关键词
D O I
暂无
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
P105
引用
收藏
页码:S38 / S38
页数:1
相关论文
共 50 条
  • [31] Blunted fasting-induced decreases in plasma and CSF leptin concentrations in obese rats: the role of increased leptin secretion
    O'Doherty, RM
    Nguyen, L
    INTERNATIONAL JOURNAL OF OBESITY, 2004, 28 (01) : 173 - 175
  • [32] Metabolic syndrome affects the retina in obese spontaneously hypertensive SHR/N-cp rats
    Huber, M.
    Sietmann, A.
    Nassar, I.
    Stoll, M.
    Kreutz, R.
    JOURNAL OF HYPERTENSION, 2008, 26 : S206 - S206
  • [33] Leptin resistance in obese transgenic rats expressing human growth hormone gene
    Furuhata, Y
    Kagaya, R
    Hirabayashi, K
    Nishihara, M
    Takahashi, M
    ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 2000, 13 : 263 - 263
  • [34] Genetic studies of the leptin receptor gene in morbidly obese French Caucasian families
    Stephan Francke
    Karine Clement
    Christian Dina
    Hiroshi Inoue
    Philip Behn
    Vincent Vatin
    Arnaud Basdevant
    Bernard Guy-Grand
    M. Alan Permutt
    Philippe Froguel
    J. Hager
    Human Genetics, 1997, 100 : 491 - 496
  • [35] Leptin receptor gene polymorphisms are associated with insulin in obese diabetic women.
    Wauters, M
    Rankinen, T
    Mertens, I
    Chagnon, M
    Bouchard, C
    Van Gaal, L
    DIABETOLOGIA, 1999, 42 : A21 - A21
  • [36] Genetic studies of the leptin receptor gene in morbidly obese French Caucasian families
    Francke, S
    Clement, K
    Dina, C
    Inoue, H
    Behn, P
    Vatin, V
    Basdevant, A
    GuyGrand, B
    Permutt, MA
    Froguel, P
    Hager, J
    HUMAN GENETICS, 1997, 100 (5-6) : 491 - 496
  • [37] Leptin resistance in diet-induced obese rats is associated with reduced leptin receptor expression and impaired signaling in the hypothalamus
    Wilsey, JT
    Zolotukhin, S
    Prima, V
    Scarpace, PJ
    FASEB JOURNAL, 2003, 17 (05): : A1043 - A1044
  • [38] Impaired neural regulation of insulin secretion related to the leptin receptor gene mutation in Wistar fatty rats
    Ohnuma, H
    Yamatani, K
    Daimon, M
    Igarashi, M
    Manaka, H
    Sasaki, H
    Kato, T
    PHYSIOLOGY & BEHAVIOR, 2000, 70 (05) : 527 - 532
  • [39] Decreased serum leptin concentration independent of dietary composition in hypertensive non obese rats.
    Duda, M
    Okere, IC
    Ernsberger, P
    Chandler, MP
    Stanley, WC
    FASEB JOURNAL, 2006, 20 (05): : A1183 - A1183
  • [40] Genes unlinked to the leptin receptor influence urinary albumin excretion in obese Zucker rats
    Kim, Kyoungmi
    Warden, Craig H.
    Griffey, Stephen M.
    Vilches-Moure, Jose G.
    Hansen, Susan
    Cuppen, Edwin
    Nijman, Isaac J.
    Chiu, Sally
    Stern, Judith S.
    PHYSIOLOGICAL GENOMICS, 2010, 41 (03) : 297 - 305