Rotavirus Genotypes in Costa Rica, Nicaragua, Honduras and the Dominican Republic

被引：17

作者：

Bourdett-Stanziola, Lurys ^{[1
,2
,3
]}

Ortega-Barria, Eduardo ^{[1
]}

Espinoza, Felix ^{[3
]}

Bucardo, Filemon ^{[3
]}

Jimenez, Carlos ^{[2
]}

Ferrera, Annabelle ^{[4
]}

机构：

[1] INDICASAT, Inst Invest Cient, Clayton, Panama

[2] Programa Invest Enfermedades Trop, Heredia, Costa Rica

[3] Univ Leon, Dept Microbiol, Leon, Nicaragua

[4] Univ Nacl Autonoma Tegucigalpa, Dept Microbiol, Tegucigalpa, Honduras

来源：

INTERVIROLOGY | 2011年 / 54卷 / 01期

关键词：

Rotavirus; Genotype; Diarrhea; VP7; VP4; RIO-DE-JANEIRO; HOSPITALIZED CHILDREN; GASTROENTERITIS;

D O I：

10.1159/000318863

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In this study, 574 stool samples from children with gastroenteritis were obtained from different hospitals in Costa Rica, Honduras, Nicaragua and the Dominican Republic during 2005-2006. Diarrhea stool samples were analyzed for rotavirus (RV) by ELISA and typed by the RT-PCR-based method. Unusual strains were detected: G1P6, G2P8, G3P6, G9P4, and mixed infections. Recent studies have indicated that unusual human RV strains are emerging as global strains, which has important implications for effective vaccine development. In this context, the next generation of RV vaccines will need to provide adequate protection against diseases caused not only by mixed infections, but also by unusual G/P combinations. Copyright (c) 2010 S. Karger AG, Basel

引用

页码：49 / 52

页数：4

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