Primary Non-Hodgkin's Lymphoma of the Vulva A Case Report and Literature Review

被引:9
|
作者
Clemente, Nicolo [1 ]
Alessandrini, Lara [2 ]
Rupolo, Maurizio [3 ]
Bulian, Pietro [4 ]
Lucia, Emilio [1 ]
Canzonieri, Vincenzo [2 ]
Sopracordevole, Francesco [1 ]
机构
[1] Natl Canc Inst, CRO Ctr Riferimento Oncol, Gynecol Oncol Unit, Via Franco Gallini, Aviano, PN, Italy
[2] Natl Canc Inst, CRO Ctr Riferimento Oncol, Div Pathol, Aviano, PN, Italy
[3] Natl Canc Inst, CRO Ctr Riferimento Oncol, Cellular Therapy & High Dose Chemotherapy Unit, Aviano, PN, Italy
[4] Natl Canc Inst, CRO Ctr Riferimento Oncol, Clin & Expt Oncohematol Unit, Aviano, PN, Italy
关键词
B-CELL LYMPHOMA; FEMALE GENITAL-TRACT; PSEUDOLYMPHOMA; CLASSIFICATION; RITUXIMAB;
D O I
10.1097/MD.0000000000003041
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The aim of this study was to add a new case of primary non-Hodgkin's malignant lymphoma of the vulva to the literature and to review the current literature. We searched the PubMed/MEDLINE databases for previous case reports using the key words "non-Hodgkin's malignant lymphoma of the vulva,'' "vulvar lymphoma,'' and "primary vulvar non-Hodgkin's lymphoma.'' We found 29 cases of primary vulvar non-Hodgkin's malignant lymphoma of the vulva reported until 2015. Among them, only 8 cases of diffuse large B-cell lymphoma (DLBCL), classified according to the most recent 2008 WHO classification, were reported. Moreover, only few studies reported the therapeutic management and clinical follow-up of patients affected by this condition. Due to its uncommon presentation, the primary non-Hodgkin's malignant lymphoma of the vulva can be undiagnosed; thus gynecologists, oncologists, and pathologists should be aware of this condition, as a correct diagnosis is essential for an appropriate therapeutic management.
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页数:5
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