Mechanism of insulin action and diabetes mellitus

[31] Disruption of the striated muscle glycogen targeting subunit PPP1R3A of protein phosphatase 1 leads to increased weight gain, fat deposition, and development of insulin resistance [J]. DIABETES, 2003, 52 (03) : 596 - 604

[32] Pten is essential for embryonic development and tumour suppression [J]. NATURE GENETICS, 1998, 19 (04) : 348 - 355

[33] DONGSHENG C, 2003, J BIOL CHEM, V278, P25323

[34] Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (35) : 32234 - 32242

[35] Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (41) : 38863 - 38869

[36] Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene [J]. SCIENCE, 1999, 283 (5407) : 1544 - 1548

[37] Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene [J]. ENDOCRINOLOGY, 1999, 140 (03) : 1329 - 1337

[38] Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis [J]. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2000, 278 (01): : E127 - E133

[39] Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes [J]. MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (01) : 319 - 329

[40] Insulin-induced stimulation of Na+,K+-ATPase activity in kidney proximal tubule cells depends on phosphorylation of the α-subunit at Tyr-10 [J]. MOLECULAR BIOLOGY OF THE CELL, 1999, 10 (09) : 2847 - 2859

[31] Disruption of the striated muscle glycogen targeting subunit PPP1R3A of protein phosphatase 1 leads to increased weight gain, fat deposition, and development of insulin resistance [J]. DIABETES, 2003, 52 (03) : 596 - 604

[32] Pten is essential for embryonic development and tumour suppression [J]. NATURE GENETICS, 1998, 19 (04) : 348 - 355

[33] DONGSHENG C, 2003, J BIOL CHEM, V278, P25323

[34] Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (35) : 32234 - 32242

[35] Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (41) : 38863 - 38869

[36] Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene [J]. SCIENCE, 1999, 283 (5407) : 1544 - 1548

[37] Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene [J]. ENDOCRINOLOGY, 1999, 140 (03) : 1329 - 1337

[38] Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis [J]. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2000, 278 (01): : E127 - E133

[39] Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes [J]. MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (01) : 319 - 329

[40] Insulin-induced stimulation of Na+,K+-ATPase activity in kidney proximal tubule cells depends on phosphorylation of the α-subunit at Tyr-10 [J]. MOLECULAR BIOLOGY OF THE CELL, 1999, 10 (09) : 2847 - 2859