Mechanism of insulin action and diabetes mellitus

[1] Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1 [J]. JOURNAL OF CLINICAL INVESTIGATION, 1998, 101 (08): : 1784 - 1788

[2] Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver [J]. NATURE, 2001, 409 (6821) : 729 - 733

[3] Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha [J]. CURRENT BIOLOGY, 1997, 7 (04) : 261 - 269

[4] 3 Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro [J]. CURRENT BIOLOGY, 1998, 8 (02) : 69 - 81

[5] ALTERNATIVE PATHWAY OF INSULIN SIGNALING IN MICE WITH TARGETED DISRUPTION OF THE IRS-1 GENE [J]. NATURE, 1994, 372 (6502) : 186 - 190

[6] Protein tyrosine phosphatases: the quest for negative regulators of insulin action [J]. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2003, 284 (04): : E663 - E670

[7] Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-λ on insulin-stimulated glucose transport in L6 myotubes [J]. ENDOCRINOLOGY, 2000, 141 (11) : 4120 - 4127

[8] Bandyopadhyay G, 1997, J BIOL CHEM, V272, P2551

[9] CAP defines a second signalling pathway required for insulin-stimulated glucose transport [J]. NATURE, 2000, 407 (6801) : 202 - 207

[10] BELKE DD, 1997, J CLIN INVEST, V273, pE59

[1] Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1 [J]. JOURNAL OF CLINICAL INVESTIGATION, 1998, 101 (08): : 1784 - 1788

[2] Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver [J]. NATURE, 2001, 409 (6821) : 729 - 733

[3] Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha [J]. CURRENT BIOLOGY, 1997, 7 (04) : 261 - 269

[4] 3 Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro [J]. CURRENT BIOLOGY, 1998, 8 (02) : 69 - 81

[5] ALTERNATIVE PATHWAY OF INSULIN SIGNALING IN MICE WITH TARGETED DISRUPTION OF THE IRS-1 GENE [J]. NATURE, 1994, 372 (6502) : 186 - 190

[6] Protein tyrosine phosphatases: the quest for negative regulators of insulin action [J]. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2003, 284 (04): : E663 - E670

[7] Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-λ on insulin-stimulated glucose transport in L6 myotubes [J]. ENDOCRINOLOGY, 2000, 141 (11) : 4120 - 4127

[8] Bandyopadhyay G, 1997, J BIOL CHEM, V272, P2551

[9] CAP defines a second signalling pathway required for insulin-stimulated glucose transport [J]. NATURE, 2000, 407 (6801) : 202 - 207

[10] BELKE DD, 1997, J CLIN INVEST, V273, pE59