The Evolution of Organ Allocation for Liver Transplantation Tackling Geographic Disparity Through Broader Sharing

被引:29
|
作者
Axelrod, David A. [1 ,2 ]
Vagefi, Parsia A. [2 ]
Roberts, John P. [3 ]
机构
[1] Dartmouth Hitchcock Med Ctr, Dept Surg, Lebanon, NH 03756 USA
[2] Massachusetts Gen Hosp, Dept Surg, Boston, MA 02114 USA
[3] Univ Calif San Francisco, Dept Surg, San Francisco, CA USA
关键词
SURVIVAL BENEFIT; OUTCOMES; RATES; MELD;
D O I
10.1097/SLA.0000000000001340
中图分类号
R61 [外科手术学];
学科分类号
摘要
The liver transplant allocation system has evolved to a ranking system of "sickest-first" system based on objective criteria. Yet, organs continue to be distributed first within OPOs and regions that are largely based on historical practice patterns related to kidney transplantation and were never designed to minimize waitlist death or equalize opportunity for liver transplant. The current proposal is a move to enhance survival though the application of modern mathematical techniques to optimize liver distribution. Like MELDbased allocation, it will never be perfect and should be continually evaluated and revised. However, the disparity in access, which favors those residing in or able to travel to privileged areas, to the detriment of the patients dying on the list in underserved areas, is simply not defensible in 2015. © 2015 Wolters Kluwer Health, Inc.
引用
收藏
页码:224 / 227
页数:4
相关论文
共 50 条
  • [31] Factors Affecting Hospital Cost After Liver Transplantation: Implications of Broader Sharing
    Ertel, Audrey
    Wima, Koffi
    Abbott, Daniel E.
    Shah, Shimul A.
    Hoehn, Richard S.
    GASTROENTEROLOGY, 2015, 148 (04) : S1181 - S1181
  • [32] Financial Impact of Liver Sharing and Organ Procurement Organizations' Experience With Share 35: Implications for National Broader Sharing
    Fernandez, H.
    Weber, J.
    Barnes, K.
    Wright, L.
    Levy, M.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2016, 16 (01) : 287 - 291
  • [33] Organ shortage and organ allocation for liver transplantation in Germany. Critical considerations
    Schlitt, H. J.
    Hackl, C.
    Knoppke, B.
    Brunner, S. M.
    Sinner, B.
    Peschel, G.
    Weigand, K.
    Melter, M.
    Scherer, M. N.
    Kirchner, G. I.
    GASTROENTEROLOGE, 2019, 14 (04): : 252 - 259
  • [34] Liver sharing and organ procurement organization performance under redistricted allocation
    Gentry, Sommer E.
    Chow, Eric K. H.
    Massie, Allan
    Luo, Xun
    Shteyn, Eugene
    Pyke, Joshua
    Zaun, David
    Snyder, Jon J.
    Israni, Ajay K.
    Kasiske, Bert
    Segev, Dorry L.
    LIVER TRANSPLANTATION, 2015, 21 (08) : 1031 - 1039
  • [35] Evolution of quality at the Organ Center of the Organ Procurement and Transplantation Network/United Network for Organ Sharing
    Brown, Roger S.
    Belton, A. Matthew
    Martin, Judith M.
    Simmons, Dee Dee
    Taylor, Gloria J.
    Willard, Ellie
    PROGRESS IN TRANSPLANTATION, 2009, 19 (03) : 221 - 226
  • [36] Liver Transplantation in Children: An Overview of Organ Allocation and Surgical Management
    Grimaldi, Chiara
    Spada, Marco
    Maggiore, Giuseppe
    CURRENT PEDIATRIC REVIEWS, 2021, 17 (04) : 245 - 252
  • [37] Simultaneous Liver Kidney Transplantation: An Organ Allocation Medical Decision
    Kiberd, Bryce
    Skedgel, Chris
    Alwayn, Ian
    Peltekian, Kevork
    AMERICAN JOURNAL OF TRANSPLANTATION, 2010, 10 : 370 - 370
  • [38] Immunosuppression, organ allocation, and other issues in liver transplantation - Foreword
    Peters, Marion
    SEMINARS IN LIVER DISEASE, 2006, 26 (03) : 199 - 200
  • [39] Summary of guidelines on organ allocation and patient listing for liver transplantation
    Keeffe, EB
    LIVER TRANSPLANTATION AND SURGERY, 1998, 4 (05): : S108 - S114
  • [40] An organ allocation system for liver transplantation based on ordinal regression
    Perez-Ortiz, M.
    Cruz-Ramirez, M.
    Ayllon-Teran, M. D.
    Heaton, N.
    Ciria, R.
    Hervas-Martinez, C.
    APPLIED SOFT COMPUTING, 2014, 14 : 88 - 98