The Evolution of Organ Allocation for Liver Transplantation Tackling Geographic Disparity Through Broader Sharing

被引:29
|
作者
Axelrod, David A. [1 ,2 ]
Vagefi, Parsia A. [2 ]
Roberts, John P. [3 ]
机构
[1] Dartmouth Hitchcock Med Ctr, Dept Surg, Lebanon, NH 03756 USA
[2] Massachusetts Gen Hosp, Dept Surg, Boston, MA 02114 USA
[3] Univ Calif San Francisco, Dept Surg, San Francisco, CA USA
关键词
SURVIVAL BENEFIT; OUTCOMES; RATES; MELD;
D O I
10.1097/SLA.0000000000001340
中图分类号
R61 [外科手术学];
学科分类号
摘要
The liver transplant allocation system has evolved to a ranking system of "sickest-first" system based on objective criteria. Yet, organs continue to be distributed first within OPOs and regions that are largely based on historical practice patterns related to kidney transplantation and were never designed to minimize waitlist death or equalize opportunity for liver transplant. The current proposal is a move to enhance survival though the application of modern mathematical techniques to optimize liver distribution. Like MELDbased allocation, it will never be perfect and should be continually evaluated and revised. However, the disparity in access, which favors those residing in or able to travel to privileged areas, to the detriment of the patients dying on the list in underserved areas, is simply not defensible in 2015. © 2015 Wolters Kluwer Health, Inc.
引用
收藏
页码:224 / 227
页数:4
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