Diet and risk of cancer of the upper aerodigestive tract - II. Nutrients

被引：94
|
作者：
De Stefani, E
Ronco, A
Mendilaharsu, M
Deneo-Pellegrini, H
机构：
[1] Registro Nacl Canc, Montevideo, Uruguay
[2] Inst Nacl Oncol, Lab Anat Patol, Montevideo, Uruguay
来源：
ORAL ONCOLOGY | 1999年 / 35卷 / 01期
关键词：
protein; total fat; cholesterol; beta-cryptoxanthine; flavonoids;
D O I：
10.1016/S1368-8375(98)00061-X
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In order to examine the risks of cancer of the upper aerodigestive tract (UADC) associated with nutrient intake, a case-control study was conducted in Uruguay in the period January 1996-December 1997. All patients afflicted with cancer of the oral cavity, pharynx, larynx, and esophagus, were included in the study. Cases were frequency-matched with hospitalized patients on age, sex, residence, and urban/rural status. A strong positive association with protein intake was observed (OR 2.5, 95% CI 1.5-4.4), whereas antioxidants were associated with an inverse association (OR for vitamin C 0.5, 95% CI 0.3-0.8). Non-nutritive substances, like flavonoids displayed a marked reduction in risk of 70%. Possible mechanisms for these findings are discussed. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：22 / 26
页数：5
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