A Neuroscience Primer for Integrating Geroscience With the Neurobiology of Aging

被引：6
|
作者：
Hernandez, Caesar M. [1 ,2 ]
Hernandez, Abigail R. [2 ,3 ]
Hoffman, Jessica M. [3 ]
King, Peter H. [1 ,4 ,5 ]
McMahon, Lori L. [1 ,2 ,6 ,7 ]
Buford, Thomas W. [2 ,3 ,6 ,7 ,8 ]
Carter, Christy [2 ,3 ]
Bizon, Jennifer L. [9 ,10 ]
Burke, Sara N. [9 ,10 ]
机构：
[1] Univ Alabama Birmingham, Dept Cellular Dev & Integrat Biol, Birmingham, AL USA
[2] Univ Alabama Birmingham, Evelyn F McKnight Brain Inst, Birmingham, AL USA
[3] Univ Alabama Birmingham, Dept Med, Div Gerontol Geriatr & Palliat Care, Birmingham, AL 35294 USA
[4] Univ Alabama Birmingham, Dept Neurol, UAB Stn, Birmingham, AL 35294 USA
[5] Birmingham Vet Affairs Med Ctr, Birmingham, AL USA
[6] Univ Alabama Birmingham, UAB Nathan Shock Ctr Basic Biol Aging, Birmingham, AL USA
[7] Univ Alabama Birmingham, UAB Integrat Ctr Aging Res, Birmingham, AL USA
[8] Birmingham VA Med Ctr, Geriatr Res Educ & Clin Ctr, Birmingham, AL USA
[9] Univ Florida, Coll Med, Dept Neurosci, Ctr Cognit Aging & Memory, Gainesville, FL 32610 USA
[10] Univ Florida, Coll Med, McKnight Brain Inst, Gainesville, FL 32610 USA
来源：
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | 2022年 / 77卷 / 01期
基金：
美国国家卫生研究院;
关键词：
Cognition; Electrophysiology; Neurobiology; Optogenetics; Pharmacology; AGE-RELATED-CHANGES; CENTRAL-NERVOUS-SYSTEM; HIPPOCAMPAL PLACE CELLS; DEEP BRAIN-STIMULATION; MEMORY IMPAIRMENT; GUT MICROBIOTA; INTESTINAL MICROBIOTA; COGNITIVE IMPAIRMENT; PREFRONTAL LESIONS; DELAYED REWARDS;
D O I：
10.1093/gerona/glab301
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Neuroscience has a rich history of studies focusing on neurobiology of aging. However, much of the aging studies in neuroscience occur outside of the gerosciences. The goal of this primer is 2-fold: first, to briefly highlight some of the history of aging neurobiology and second, to introduce to geroscientists the broad spectrum of methodological approaches neuroscientists use to study the neurobiology of aging. This primer is accompanied by a corresponding geroscience primer, as well as a perspective on the current challenges and triumphs of the current divide across these 2 fields. This series of manuscripts is intended to foster enhanced collaborations between neuroscientists and geroscientists with the intent of strengthening the field of cognitive aging through inclusion of parameters from both areas of expertise.
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页码：E19 / E33
页数：15
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