A new neolignan and antioxidant Phenols from Nectandra grandiflora

被引：39

作者：

Ribeiro, AB

Bolzani, VD

Yoshida, M

Santos, LS

Eberlin, MN

Silva, DHS

机构：

[1] Univ Estadual Paulista, Inst Quim, BR-14801900 Araraquara, SP, Brazil

[2] Univ Sao Paulo, Inst Quim, BR-05513970 Sao Paulo, Brazil

[3] Inst Pesquisas Amazonia, BR-69083000 Manaus, Amazonas, Brazil

[4] Univ Estadual Campinas, Inst Quim, BR-13084971 Campinas, SP, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2005年 / 16卷 / 3B期

关键词：

Nectandra grandiflora; Lauraceae; neolignan; flavonoid; radical scavenging activity; antioxidant;

D O I：

10.1590/S0103-50532005000400005

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The EtOH crude extract from the leaves of Nectandra grandiflora collected in the Atlantic Forest, Brazil, showed antioxidant activity towards beta-carotene in a TLC assay. The bioassay-guided fractionation led to the isolation of protocatechuic acid and two flavonol glycosides: afzelin and quercetrin, which showed free radical scavenging activity towards DPPH (Delta A 32, 16 and 73% at 50 mu mol L-1) and were compared to commercial antioxidants rutin (81% at 50 mu mol L-1) and BHT (9% at 50 mu mol L-1), used as standard compounds. Additionally, three inactive neolignans, including the new bicycle[3.2.1] octane neolignan 2'-oxo-piperol B were obtained and characterized by spectrometric methods.

引用

页码：526 / 530

页数：5

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