Recently, stem cell biology has become an interesting topic. Several varieties of human stem cells have been isolated and identified in vivo and in vitro. Successful application of hematopoietic stem cells in hematology has led to the search for other sources of stem cells and expanding the scale of their application. Perinatal stem cells are a versatile cell population, and they are interesting for both scientific and practical objectives. Stem cells from perinatal tissue may be particularly useful in the clinic for autologous transplantation for fetuses and newborns, and after banking in later stages of life, as well as for in utero transplantation in the case of genetic disorders. In this review paper we focus on the extraction and therapeutic potential of stem cells derived from perinatal tissues such as the placenta, the amnion, amniotic fluid, umbilical cord blood and Wharton's jelly.
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Pontificia Univ Catolica Rio Grande do Sul, Programa Posgrad Saude Crianca, BR-90619900 Porto Alegre, RS, BrazilPontificia Univ Catolica Rio Grande do Sul, InsCer, Lab Neurociencias, BR-90619900 Porto Alegre, RS, Brazil
de Paula, Simone
Greggio, Samuel
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Pontificia Univ Catolica Rio Grande do Sul, Programa Posgrad Saude Crianca, BR-90619900 Porto Alegre, RS, BrazilPontificia Univ Catolica Rio Grande do Sul, InsCer, Lab Neurociencias, BR-90619900 Porto Alegre, RS, Brazil
Greggio, Samuel
DaCosta, Jaderson Costa
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Pontificia Univ Catolica Rio Grande do Sul, InsCer, Lab Neurociencias, BR-90619900 Porto Alegre, RS, Brazil
Pontificia Univ Catolica Rio Grande do Sul, Fac Med, BR-90619900 Porto Alegre, RS, BrazilPontificia Univ Catolica Rio Grande do Sul, InsCer, Lab Neurociencias, BR-90619900 Porto Alegre, RS, Brazil
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FRED HUTCHINSON CANC RES CTR,PROGRAM TRANSPLANTAT BIOL,1124 COLUMBIA ST M318,SEATTLE,WA 98104FRED HUTCHINSON CANC RES CTR,PROGRAM TRANSPLANTAT BIOL,1124 COLUMBIA ST M318,SEATTLE,WA 98104
HONG, DS
DEEG, HJ
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FRED HUTCHINSON CANC RES CTR,PROGRAM TRANSPLANTAT BIOL,1124 COLUMBIA ST M318,SEATTLE,WA 98104FRED HUTCHINSON CANC RES CTR,PROGRAM TRANSPLANTAT BIOL,1124 COLUMBIA ST M318,SEATTLE,WA 98104