N-(DIPHENOXYPHOSPHORYL)SUCCINIMIDE: SYNTHESIS AND REACTION WITH ALKOXIDES

被引：0
|
作者：
Andruszkiewicz, Ryszard [1 ]
Liedke-Przybysz, Ewa [1 ]
机构：
[1] Gdansk Univ Technol, Dept Pharmaceut Technol & Biochem, Gdansk, Poland
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2011年 / 186卷 / 12期
关键词：
Phosphorylated succinimide; nucleophilic ring opening; phosphoramidates; N-PHOSPHORYL OXAZOLIDINONES; AGENTS;
D O I：
10.1080/10426507.2011.608098
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Reaction of succinimide with diphenylchlorophosphate in the presence of lithium bis(trimethylsilyl)amide followed by aqueous work-up led to the formation of amidophosphate 3. The same reaction performed in the presence of sodium hydride yield N-(diphenylphosphoryl)succinimde 4, which undergoes nucleophilic ring opening with sodium alkoxides resulted in the formation of phosphoroamidate analogues 5 a-d in good yields.
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收藏
页码：2274 / 2278
页数：5
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