Iodine-catalyzed α,β-dehydrogenation of ketones and aldehydes generating conjugated enones and enals

被引：14
|
作者：
Cao, Yuanjie [1 ]
Liu, Long [2 ]
Huang, Tianzeng [2 ]
Chen, Tieqiao [1 ,2 ]
机构：
[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China
[2] Hainan Univ, Key Lab, Minist Educ Adv Mat Trop Isl Resources, Coll Chem Engn & Technol, Haikou 570228, Hainan, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2020年 / 44卷 / 21期
关键词：
ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; DIELS-ALDER REACTION; SILYL ENOL ETHERS; ONE-POT SYNTHESIS; SELECTIVE OXIDATION; ALPHA-KETOAMIDES; DEHYDROGENATION; ACID; CONVERSION; ALCOHOLS;
D O I：
10.1039/d0nj01244k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A transition metal-free alpha,beta-dehydrogenation of ketones and aldehydes was developed. This reaction was conducted in a facile I-2/KI/DMSO system to produce the corresponding unsaturated compounds in good to high yields. The gram-scale experiment also indicated the potential synthetic value of this new reaction in organic synthesis. In the reaction, DMSO acted as both solvent and mild oxidant.
引用
收藏
页码：8697 / 8701
页数：5
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