Iodine-catalyzed α,β-dehydrogenation of ketones and aldehydes generating conjugated enones and enals

被引：14

作者：

Cao, Yuanjie ^{[1
]}

Liu, Long ^{[2
]}

Huang, Tianzeng ^{[2
]}

Chen, Tieqiao ^{[1
,2
]}

机构：

[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China

[2] Hainan Univ, Key Lab, Minist Educ Adv Mat Trop Isl Resources, Coll Chem Engn & Technol, Haikou 570228, Hainan, Peoples R China

来源：

NEW JOURNAL OF CHEMISTRY | 2020年 / 44卷 / 21期

关键词：

ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; DIELS-ALDER REACTION; SILYL ENOL ETHERS; ONE-POT SYNTHESIS; SELECTIVE OXIDATION; ALPHA-KETOAMIDES; DEHYDROGENATION; ACID; CONVERSION; ALCOHOLS;

D O I：

10.1039/d0nj01244k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A transition metal-free alpha,beta-dehydrogenation of ketones and aldehydes was developed. This reaction was conducted in a facile I-2/KI/DMSO system to produce the corresponding unsaturated compounds in good to high yields. The gram-scale experiment also indicated the potential synthetic value of this new reaction in organic synthesis. In the reaction, DMSO acted as both solvent and mild oxidant.

引用

页码：8697 / 8701

页数：5

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