Total synthesis of (+)-aspergillide C

被引：22
|
作者：
Kanematsu, Makoto [1 ]
Yoshida, Masahiro [1 ]
Shishido, Kozo [1 ]
机构：
[1] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan
来源：
TETRAHEDRON LETTERS | 2011年 / 52卷 / 12期
关键词：
CYTOTOXIC 14-MEMBERED MACROLIDES; ENANTIOSELECTIVE TOTAL-SYNTHESIS; ASPERGILLIDE; EPOXIDES; GENERATION; OXIRANES;
D O I：
10.1016/j.tetlet.2011.01.078
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The enantioselective total synthesis of aspergillide C. a member of a novel class of 14-membered macro-lides isolated from the marine-derived fungus Aspergillus ostionus strain 01F313, has been accomplished employing a highly diastereoselective intramolecular oxy-Michael reaction as the key step. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1372 / 1374
页数：3
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