Chemical modelling of quantitative spin trapping under in vitro conditions.

被引:0
|
作者
Shutova, T [1 ]
Kriska, T [1 ]
Németh, A [1 ]
Gál, D [1 ]
机构
[1] MTA Kemiai Kutatokozpont, Kemiai Intezet, H-1525 Budapest, Hungary
来源
MAGYAR KEMIAI FOLYOIRAT | 2001年 / 107卷 / 04期
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中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In order to apply spin trapping for biological purposes where the appropriate spin traps yield adducts with short lifetimes, a method has been elaborated according to which the accumulation of the adducts was followed by kinetic ESR spectroscopy. It has been assumed that in the early stages of the accumulation the consumption of the adduct is negligible enabling the determination of the rate constants of the spin trapping steps completed for four various peroxy radicals.
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页码:161 / 166
页数:6
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