Biological variation for N-terminal pro- and B-type natriuretic peptides and implications for therapeutic monitoring of patients with congestive heart failure

被引：210

作者：

Wu, AHB

Smith, A

Wieczorek, S

Mather, JF

Duncan, B

White, CM

McGill, C

Katten, D

Heller, G

机构：

[1] Hartford Hosp, Div Pathol & Lab Med, Dept Pathol & Lab Med, Hartford, CT 06102 USA

[2] Hartford Hosp, Dept Res, Hartford, CT 06102 USA

[3] Henry Low Heart Ctr, Dept Med, Div Cardiol, Hartford, CT USA

[4] Univ Connecticut, Sch Pharm, Storrs, CT USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2003年 / 92卷 / 05期

关键词：

D O I：

10.1016/S0002-9149(03)00741-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Given the limitations of low enrollments, this study suggests that a change of 130% for B-type natiuretic peptide (BHP) and 90% for N-terminal (NT) -proBNP are necessary before results of serially collected data can be considered statistically different. This study also shows that there are important differences in the performance of BNP versus NT-proBNP in monitoring patients with congestive heart failure that need to be further explored. (C) 2003 by Excerpta Medica, Inc.

引用

页码：628 / 631

页数：4

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