Pd nanoparticles catalyst supported on TMU-16-NH2 metal-organic framework for Sonogashira cross-coupling reaction

The current article presented the synthesis and characterization of a novel, unique, and effective heterogeneous catalytic system, based on a metal-organic framework named Pd@TMU-16-NH2 with high catalytic performance. Also, the application of this catalyst was investigated successfully in the Sonogashira coupling reaction of various aryl halides (I, Br, Cl) with phenylacetylene. This reaction was carried out in EtOH with good to excellent yields in the presence of just 1.5 mol% of the catalyst under mild conditions. Stability, recovery, reusability, high yield products, and short reaction time are some of the noteworthy characteristics of the Pd@TMU-16-NH2 nanocatalyst. These properties can decrease pollution to obtain the standards of green chemistry. (C) 2021 Published by Elsevier B.V.