The incidence and survival outcomes of patients with primary cardiac lymphoma: A SEER-based analysis

被引:13
|
作者
Xiao, Min [1 ,2 ]
Lin, Junpeng [3 ]
Xiao, Tingting [4 ]
Lin, Yan [1 ,2 ]
Ye, Yong [1 ,2 ]
机构
[1] Fujian Canc Hosp, Dept Intens Care Unit, 420 Fuma Rd, Fuzhou 350014, Fujian, Peoples R China
[2] Fujian Med Univ, 420 Fuma Rd, Fuzhou 350014, Fujian, Peoples R China
[3] Fujian Med Univ, Dept Gastr Surg, Union Hosp, Fuzhou, Peoples R China
[4] Fujian Med Univ, Union Hosp, Fujian Prov Key Lab Hematol, Dept Hematol,Fujian Inst Hematol, Fuzhou, Peoples R China
关键词
cardiac neoplasms; population characteristics; prognosis; SEER program; therapy; CLINICAL-PRACTICE GUIDELINES; DIAGNOSIS; RESECTION;
D O I
10.1002/hon.2741
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This study aimed to evaluate the incidence and prognosis of primary cardiac lymphoma (PCL) by using the Surveillance, Epidemiology, and End Results Program (SEER) database. Patients diagnosed with PCL and the disease incidence in the SEER database from 1975 to 2016 were included. Overall survival (OS) and cause-specific survival (CSS) curves were calculated using the Kaplan-Meier method and compared by the log-rank test. Univariate and multivariable Cox proportional hazard regression analyses were used to identify associations with outcome measures. The incidence of PCL was 0.011/100 000, and a predominance of elderly and male patients was observed. A total of 144 patients were enrolled. The median age of onset was 68 (9-96) years, including 80 (55.6%) males and 64 (44.4%) females. Multivariate analysis revealed that age and chemotherapy were independent prognostic factors for OS (both P < .05). Ann Arbor stage and chemotherapy were independent prognostic factors for CSS (both P < .05). In terms of treatment modality, chemotherapy combined with surgery was an independent protective factor for OS and CSS (both P < .05). For patients with primary cardiac diffuse large B-cell lymphoma (cardiac DLBCL), multivariate analysis also showed that age, Ann Arbor stage, and chemotherapy were all independent prognostic factors for OS and CSS (all P < .05). Chemotherapy combined with surgery was associated with a significant benefit in terms of OS and CSS (both P < .05). Our study confirmed that older age and advanced Ann Arbor stage were independent risk factors for PCL, and treatment with chemotherapy or cooperation with surgery resulted in better long-term survival.
引用
收藏
页码:334 / 343
页数:10
相关论文
共 50 条
  • [21] Comparison of the Effect of Chemoradiotherapy and Chemotherapy on the Survival of Patients with Primary Diffuse Large B-Cell Lymphoma of the Spine: A SEER-Based Study
    Cao, Shuyan
    Fan, Bingjie
    Sun, Qifeng
    Chen, Jianxing
    Song, Xin
    Yin, Wenzhe
    WORLD NEUROSURGERY, 2023, 175 : E940 - E949
  • [22] Improved survival of patients with stage III small-cell lung cancer with primary resection: A SEER-based analysis
    Jia, Jianlong
    Trassl, Lilith
    Kong, Fanli
    Deng, Benteng
    Liu, Ruonan
    Sun, Zhengwu
    Lan, Xiaoyan
    Yildirim, Ali Oe
    Stathopoulos, Georgios T.
    Fernandez, Isis E.
    Schamberger, Andrea C.
    TRANSLATIONAL ONCOLOGY, 2024, 49
  • [23] Prognostic modeling of overall survival and analysis of K-M survival curves in patients with primary colon cancer: A SEER-based study
    Li, Chongyang
    Cao, Shengqin
    Sun, Xuedi
    Lu, Chunlei
    Guo, Mingxiao
    MEDICINE, 2023, 102 (23)
  • [24] Epidemiologic Characteristics, Prognostic Factors, and Treatment Outcomes in Primary Central Nervous System Lymphoma: A SEER-Based Study
    Tang, Dongsheng
    Chen, Yue
    Shi, Yuye
    Tao, Hong
    Tao, Shandong
    Zhang, Quan'e
    Ding, Banghe
    He, Zhengmei
    Yu, Liang
    Wang, Chunling
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [25] Survival Trends in Patients Under Age 65 Years With Mantle Cell Lymphoma, 1995-2016: A SEER-Based Analysis
    Wu, Hongyu
    Wang, Jianwei
    Zhang, Xuanye
    Yang, Hang
    Wang, Yu
    Sun, Peng
    Cai, Qingqing
    Xia, Yi
    Liu, Panpan
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [26] Incidence of adrenal gland tumor as a second primary malignancy: SEER-based study
    Rashed, Wafaa M.
    Saad, Anas
    Al-Husseini, Muneer
    Galal, Ahmed Mahmoud
    Ismael, Assem Mohamed
    Al-Tayep, Ahmed M.
    El Shafie, Ayman
    Ali, Mahmoud Ahmed
    Alfaar, Ahmad Samir
    ENDOCRINE CONNECTIONS, 2018, 7 (10): : 1040 - 1048
  • [27] Frequency, incidence and survival outcomes of clear cell renal cell carcinoma in the United States from 1973 to 2014 A SEER-based analysis
    Feng, Xiao
    Zhang, Lina
    Tu, Wenzhi
    Cang, Shundong
    MEDICINE, 2019, 98 (31)
  • [28] Characteristics, survival and incidence rates and trends of pilocytic astrocytoma in children in the United States; SEER-based analysis
    Tabash, Mohamed A.
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2019, 400 : 148 - 152
  • [29] Risk of Multiple Primary Cancers in Patients With Merkel Cell Carcinoma A SEER-Based Analysis
    Eid, Edward
    Maloney, Nolan J.
    Cai, Zhuo Ran
    Zaba, Lisa C.
    Kibbi, Nour
    John, Esther M.
    Linos, Eleni
    JAMA DERMATOLOGY, 2023, 159 (11) : 1248 - 1252
  • [30] The incidence, prognosis and survival of primary breast lymphoma: A SEER experience.
    Kumar, Vivek
    Singh, Prabhsimranjot
    Shrivastava, Makardhwaj
    Chandra, Abhinav Binod
    Xu, Yiqing
    Solomon, William B.
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)