Determination of astragalosides in the roots of Astragalus spp. using liquid chromatography tandem atmospheric pressure chemical ionization mass spectrometry

被引：33
|
作者：
Xu, Qing [1 ]
Ma, Xiaoqiong [1 ]
Liang, Xinmiao [1 ]
机构：
[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
来源：
PHYTOCHEMICAL ANALYSIS | 2007年 / 18卷 / 05期
关键词：
HPLC-APCI-MS; astragalosides; astragalus mongholicus; astragalus membranceus;
D O I：
10.1002/pca.997
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A high-performance liquid chromatography tandem atmospheric pressure chemical ionization mass spectrometry method (HPLC-APCI-MS) has been developed for the characterization of astragalosides in the extracts of the roots of Astragalus spp. The [M - H](-) ions of astragalosides could be clearly observed in selected ion monitoring mode and APCI-MS-MS was used to further identify the structures of the astragalosides. Twelve astragalosides in the extracts of Radix Astragali obtained from Shandong in China were separated and identified. Using this method, astragalosides could be clearly identified and the profiles of these astragalosides could also be used to distinguish Astragalus spp. from different habitat regions. Copyright (c) 2007 John Wiley & Sons, Ltd.
引用
收藏
页码：419 / 427
页数：9
相关论文
共 50 条
  • [41] Atmospheric pressure chemical ionization tandem mass spectrometry of carotenoids
    van Breemen, Richard B.
    Dong, Linlin
    Pajkovic, Natasa D.
    INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2012, 312 : 163 - 172
  • [42] Molecular species of sphingomyelin:: Determination by high-performance liquid chromatography mass spectrometry with electrospray and high-performance liquid chromatography tandem mass spectrometry with atmospheric pressure chemical ionization
    Karlsson, AÅ
    Michélsen, P
    Odham, G
    JOURNAL OF MASS SPECTROMETRY, 1998, 33 (12): : 1192 - 1198
  • [43] Pharmacokinetics of ergosterol in rats using rapid resolution liquid chromatography-atmospheric pressure chemical ionization multi-stage tandem mass spectrometry and rapid resolution liquid chromatography/tandem mass spectrometry
    Zhao, Ying-Yong
    Cheng, Xian-Long
    Liu, Rui
    Ho, Charlene C.
    Wei, Feng
    Yan, Sui-Hong
    Lin, Rui-Chao
    Zhang, Yongmin
    Sun, Wen-Ji
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2011, 879 (21): : 1945 - 1953
  • [44] Analysis of avermectin and moxidectin residues in milk by liquid chromatography-tandem mass spectrometry using an atmospheric pressure chemical ionization/atmospheric pressure photoionization source
    Turnipseed, SB
    Roybal, JE
    Andersen, WC
    Kuck, LR
    ANALYTICA CHIMICA ACTA, 2005, 529 (1-2) : 159 - 165
  • [45] Characterization of the chemical composition of a block copolymer by liquid chromatography/mass spectrometry using atmospheric pressure chemical ionization and electrospray ionization
    van Leeuwen, Suze M.
    Tan, BoonHua
    Grijpma, Dirk W.
    Fejen, Jan
    Karst, Uwe
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2007, 21 (16) : 2629 - 2637
  • [46] Quantification of 17β-estradiol residues in bovine serum by liquid chromatography tandem mass spectrometry with atmospheric pressure chemical ionization
    Draisci, R
    Palleschi, L
    Ferretti, E
    Marchiafava, C
    Lucentini, L
    Cammarata, P
    ANALYST, 1998, 123 (12) : 2605 - 2609
  • [47] Development of liquid chromatography atmospheric pressure chemical ionization tandem mass spectrometry for analysis of halogenated flame retardants in wastewater
    Simon Ningsun Zhou
    Eric J. Reiner
    Chris Marvin
    Paul Helm
    Nicole Riddell
    Frank Dorman
    Michelle Misselwitz
    Li Shen
    Patrick Crozier
    Karen MacPherson
    Ian D. Brindle
    Analytical and Bioanalytical Chemistry, 2010, 396 : 1311 - 1320
  • [48] Quantification of tripdiolide in human whole blood by liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry
    Jin, Micong
    OuYang, Xiaokun
    Yang, Yiwen
    Ren, Qilong
    TALANTA, 2007, 72 (02) : 582 - 586
  • [49] Characterization of polymethoxylated flavones in Fructus aurantii by liquid chromatography with atmospheric pressure chemical ionization combined with tandem mass spectrometry
    Zhou, Da-Yong
    Chen, De-Liang
    Xu, Qing
    Xue, Xing-Ya
    Zhang, Fei-Fang
    Liang, Xin-Miao
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2007, 43 (05) : 1692 - 1699
  • [50] Application of atmospheric pressure ionization liquid chromatography tandem mass spectrometry for the analysis of flavor precursors
    Herderich, M
    Roscher, R
    Schreier, P
    BIOTECHNOLOGY FOR IMPROVED FOODS AND FLAVORS, 1996, 637 : 261 - 271
12345