A functionalized fluorescent dendrimer as a pesticide nanocarrier: application in pest control

被引：56
|
作者：
Liu, Xiaoxia [1 ]
He, Bicheng [1 ]
Xu, Zejun [2 ]
Yin, Meizhen [2 ]
Yang, Wantai [2 ]
Zhang, Huaijiang [1 ]
Cao, Jingjun [1 ]
Shen, Jie [1 ]
机构：
[1] China Agr Univ, Dept Entomol, Beijing 100193, Peoples R China
[2] Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Key Lab Carbon Fiber & Funct Polymers, Minist Educ,Beijing Lab Biomed Mat, Beijing 100029, Peoples R China
来源：
NANOSCALE | 2015年 / 7卷 / 02期
基金：
北京市自然科学基金; 美国国家科学基金会;
关键词：
DRUG-DELIVERY; NANOPARTICLES; RELEASE; THERAPEUTICS; THIAMETHOXAM; COVALENT; CARRIERS; DNA;
D O I：
10.1039/c4nr05733c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report the delivery of a hydrophobic pesticide, thiamethoxam, by water-soluble nanosized cationic dendrimers that contain hydrophobic dendritic polyesters and peripheral amines, demonstrated by DLS, spectral analysis and ITC. The dendrimer-based nanocarrier can efficiently deliver the pesticide into the live cells and largely increase the cytotoxicity of the drug.
引用
收藏
页码：445 / 449
页数：5
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