Sotorasib in combination with panitumumab in refractory KRAS G12C-mutated colorectal cancer: Safety and efficacy for phase Ib full expansion cohort

被引:15
|
作者
Kuboki, Y. [1 ]
Yaeger, R. [2 ]
Fakih, M. G. [3 ]
Strickler, J. H. [4 ]
Masuishi, T. [5 ]
Kim, E. J. [6 ]
Bestvina, C. M. [7 ]
Langer, C. J. [8 ]
Krauss, J. C. [9 ]
Puri, S. [10 ]
Cardona, P. [11 ]
Chan, E. [12 ]
Tran, Q. [12 ]
Hong, D. S. [13 ]
机构
[1] Natl Canc Ctr Hosp East, Expt Therapeut & GI Oncol Dept, Kashiwa, Japan
[2] Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY USA
[3] City Hope Comprehens Canc Ctr, Med Oncol & Therapeut Res, Duarte, CA USA
[4] Duke Univ, Dept Med, Med Ctr, Durham, NC USA
[5] Aichi Canc Ctr Hosp, Clin Oncol Dept, Nagoya, Aichi, Japan
[6] UC Davis Comprehens Canc Ctr, Hematol Oncol Internal Med, Sacramento, CA USA
[7] Univ Chicago, Dept Med, Sect Hematol Oncol, Chicago, IL USA
[8] Univ Penn, Hematol Oncol, Philadelphia, PA USA
[9] Univ Michigan, Hematol Oncol Internal Med, Ann Arbor, MI USA
[10] Huntsman Canc Inst, Med Hematol & Oncol, Salt Lake City, UT USA
[11] Amgen Inc, Clin Pharmacol Modeling & Simulat, Thousand Oaks, CA USA
[12] Amgen Inc, Res & Dev, Thousand Oaks, CA USA
[13] Univ Texas MD Anderson Canc Ctr, Invest Canc Therapeut, Houston, TX USA
关键词
D O I
10.1016/j.annonc.2022.07.453
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
315O
引用
收藏
页码:S680 / S681
页数:2
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