"Turn-on" FRET-based luminescent iridium(III) probes for the detection of cysteine and homocysteine

被引：81
|
作者：
Shiu, Hoi-Yan [2 ,3 ]
Wong, Man-Kin [1 ]
Che, Chi-Ming [2 ,3 ]
机构：
[1] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China
[2] Univ Hong Kong, Dept Chem, State Key Lab Synthet Chem, Hong Kong, Hong Kong, Peoples R China
[3] Univ Hong Kong, Open Lab Chem Biol, Inst Mol Technol Drug Discovery & Synth, Hong Kong, Hong Kong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 15期
关键词：
RESONANCE ENERGY-TRANSFER; CYCLOMETALATED PLATINUM(II) COMPLEXES; BIOLOGICAL LABELING REAGENTS; PROTEIN-BINDING; SWITCH; CHROMOPHORES; DISEASE; DONOR; DYES;
D O I：
10.1039/c0cc04288a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
"Turn-on" FRET-based luminescent probes containing iridium(III) complexes for the detection of Cys and Hcy have been designed and synthesized. The relationship between the steric bulk of the probe and the corresponding emission intensity enhancement towards detection of Cys and Hcy has been studied.
引用
收藏
页码：4367 / 4369
页数：3
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