Correlation with redox potentials and inhibitory effects on Epstein-Barr virus activation of azaanthraquinones

被引：18
|
作者：
Koyama, J [1 ]
Morita, I
Tagahara, K
Osakai, T
Hotta, H
Yang, MX
Mukainaka, T
Nishino, H
Tokuda, H
机构：
[1] Kobe Pharmaceut Univ, Higashinada Ku, Kobe, Hyogo 6588558, Japan
[2] Kobe Univ, Fac Sci, Dept Chem, Kobe, Hyogo 6578501, Japan
[3] Kyoto Prefectural Univ Med, Dept Biochem, Kyoto 6028566, Japan
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2001年 / 49卷 / 09期
关键词：
azaanthraquinone; Epstein-Barr virus activation; redox potential; cyclic voltammetry; anti-tumor promoting effect;
D O I：
10.1248/cpb.49.1214
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
means of cyclic voltammetry. A definite correlation has been found between the redox potentials and the inhibitory effects of the azaanthraquinones on Epstein-Barr virus early antigen (EBV-EA) activation. It has further been shown that the correlation can be made better by introducing an electronic property, i.e., the atomic charge at O-11 as an additional parameter.
引用
收藏
页码：1214 / 1216
页数：3
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