Cobalt-catalyzed alkylation of methyl-substituted N-heteroarenes with primary alcohols: direct access to functionalized N-heteroaromatics

被引：26
|
作者：
Mishra, Anju [1 ]
Dwivedi, Ambikesh D. [1 ]
Shee, Sujan [1 ]
Kundu, Sabuj [1 ]
机构：
[1] Indian Inst Technol Kanpur, Dept Chem, Kanpur 208016, Uttar Pradesh, India
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 02期
关键词：
SECONDARY ALCOHOLS; HYDROGENATION; STRATEGY; METALS; IRON; CHEMISTRY; EARTH; FE; CO;
D O I：
10.1039/c9cc08448g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Phosphine free, air and moisture stable Co(NNN) complex catalyzed alkylation of various methyl-substituted N-heteroarenes with alcohols is reported. Following the borrowing hydrogen methodology, a variety of methyl-substituted N-heteroarenes can be functionalized efficiently. To understand the mechanism of this reaction various kinetic and control experiments were carried out.
引用
收藏
页码：249 / 252
页数：4
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