Miscarriage and Stillbirth in Women with Rheumatoid Arthritis

被引:28
|
作者
Wallenius, Marianne [1 ]
Salvesen, Kjell A. [2 ]
Daltveit, Anne K. [3 ,4 ]
Skomsvoll, Johan F. [1 ]
机构
[1] Trondheim Reg & Univ Hosp, Natl Advisory Unit Pregnancy & Rheumat Dis, Dept Rheumatol, N-7006 Trondheim, Norway
[2] Trondheim Reg & Univ Hosp, Natl Ctr Fetal Med, Dept Obstet & Gynecol, N-7006 Trondheim, Norway
[3] Univ Bergen, Dept Global Publ Hlth & Primary Care, N-5020 Bergen, Norway
[4] Norwegian Inst Publ Hlth, Div Epidemiol, MBRN, Bergen, Norway
关键词
RHEUMATOID ARTHRITIS; SPONTANEOUS ABORTION; STILLBIRTH; EPIDEMIOLOGIC STUDY; BIRTH REGISTRY; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; MEDICAL BIRTH REGISTRY; PREGNANCY; OUTCOMES; RISK; DISEASE; NORWAY;
D O I
10.3899/jrheum.141553
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective. To examine the risk of pregnancy loss in women with rheumatoid arthritis (RA). Methods. Cumulative numbers of early miscarriages (before gestational Week 12), late miscarriages (weeks 12-22), and stillbirths reported to the Medical Birth Registry of Norway in the period 1999-2009. Results. There were 1578 women with RA and 411,130 reference women included in the study. Relative risks of early and late miscarriage in women with RA versus references were 1.2 (95% CI 1.1-1.3) and 1.4 (95% CI 1.1-1.7), respectively. There was no difference in stillbirth. Conclusion. The risk of miscarriage was slightly higher among women with RA than in references.
引用
收藏
页码:1570 / 1572
页数:3
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