Never Waste a Good Crisis: Confronting Reproducibility in Translational Research

被引:83
|
作者
Drucker, Daniel J. [1 ]
机构
[1] Univ Toronto, Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Dept Med, Toronto, ON M5G 1X5, Canada
关键词
BETA-CELL PROLIFERATION; HIGH-FAT DIET; TARGETING INFLAMMATION; PRECLINICAL RESEARCH; INSULIN-RESISTANCE; BODY-WEIGHT; MICE; TAMOXIFEN; ANTIBODY; ATHEROSCLEROSIS;
D O I
10.1016/j.cmet.2016.08.006
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The lack of reproducibility of preclinical experimentation has implications for sustaining trust in and ensuring the viability and funding of the academic research enterprise. Here I identify problematic behaviors and practices and suggest solutions to enhance reproducibility in translational research.
引用
收藏
页码:348 / 360
页数:13
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