Never Waste a Good Crisis: Confronting Reproducibility in Translational Research

被引：83

作者：

Drucker, Daniel J. ^{[1
]}

机构：

[1] Univ Toronto, Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Dept Med, Toronto, ON M5G 1X5, Canada

来源：

CELL METABOLISM | 2016年 / 24卷 / 03期

关键词：

BETA-CELL PROLIFERATION; HIGH-FAT DIET; TARGETING INFLAMMATION; PRECLINICAL RESEARCH; INSULIN-RESISTANCE; BODY-WEIGHT; MICE; TAMOXIFEN; ANTIBODY; ATHEROSCLEROSIS;

D O I：

10.1016/j.cmet.2016.08.006

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The lack of reproducibility of preclinical experimentation has implications for sustaining trust in and ensuring the viability and funding of the academic research enterprise. Here I identify problematic behaviors and practices and suggest solutions to enhance reproducibility in translational research.

引用

页码：348 / 360

页数：13

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