Cloning and mapping of a human novel cDNA (NHP2L1) that encodes a protein highly homologous to yeast nuclear protein NHP2

被引：17
|
作者：
Saito, H
Fujiwara, T
Shin, S
Okui, K
Nakamura, Y
机构：
[1] UNIV TOKYO,INST MED SCI,MOLEC MED LAB,MINATO 108,JAPAN
[2] INST CANC RES,DEPT BIOCHEM,TOKYO,JAPAN
[3] OTSUKA PHARMACEUT CO LTD,OTSUKA GEN INST,TOKUSHIMA 77101,JAPAN
来源：
CYTOGENETICS AND CELL GENETICS | 1996年 / 72卷 / 2-3期
关键词：
D O I：
10.1159/000134186
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
We have isolated a novel human cDNA that encodes a protein highly homologous to NHP2, a nuclear protein of yeast, that is thought to have an essential physiological function for cell viability. The 1,493-bp cDNA sequence includes an open reading frame of 384 bp. This gene (NHP2L1) was expressed in all human tissues examined, and was localized to chromosome band 12q24.3 by fluorescence in situ hybridization.
引用
收藏
页码：191 / 193
页数：3
相关论文
共 50 条
  • [1] Isolation and mapping of RAB2L, a human cDNA that encodes a protein homologous to RaIGDS
    Isomura, M
    Okui, K
    Fujiwara, T
    Shin, S
    Nakamura, Y
    [J]. CYTOGENETICS AND CELL GENETICS, 1996, 74 (04): : 263 - 265
  • [2] Molecular cloning and mapping of a human cDNA (PA2G4) that encodes a protein highly homologous to the mouse cell cycle protein p38-2G4
    Lamartine, J
    Seri, M
    Cinti, R
    Heitzmann, F
    Creaven, M
    Radomski, N
    Jost, E
    Lenoir, GM
    Romeo, G
    Sylla, BS
    [J]. CYTOGENETICS AND CELL GENETICS, 1997, 78 (01): : 31 - 35
  • [3] In silico analysis of NHP2 membrane protein, a novel vaccine candidate present in the RD7 region of Mycobacterium tuberculosis
    Kootery, Kaviya Parambath
    Sarojini, Suma
    [J]. BIOLOGIA, 2024, 79 (01) : 355 - 372
  • [4] In silico analysis of NHP2 membrane protein, a novel vaccine candidate present in the RD7 region of Mycobacterium tuberculosis
    Kaviya Parambath Kootery
    Suma Sarojini
    [J]. Biologia, 2024, 79 : 355 - 372
  • [5] CLONING BY DIFFERENTIAL SCREENING OF A XENOPUS CDNA CODING FOR A PROTEIN HIGHLY HOMOLOGOUS TO CDC2
    PARIS, J
    LEGUELLEC, R
    COUTURIER, A
    LEGUELLEC, K
    OMILLI, F
    CAMONIS, J
    MACNEILL, S
    PHILIPPE, M
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (03) : 1039 - 1043
  • [6] Expression of the human homologue of the small nucleolar RNA-binding protein NHP2 gene during monocytic differentiation of U937 cells
    Kang, HS
    Jung, HM
    Jun, DY
    Huh, TL
    Kim, YH
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 2002, 1575 (1-3): : 31 - 39
  • [7] CHARACTERIZATION BY CDNA CLONING OF THE MESSENGER-RNA OF A HIGHLY BASIC HUMAN PROTEIN HOMOLOGOUS TO THE YEAST RIBOSOMAL-PROTEIN YL41
    KLAUDINY, J
    VONDERKAMMER, H
    SCHEIT, KH
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 187 (02) : 901 - 906
  • [8] SEQUENCE AND GENETIC-ANALYSIS OF NHP2 - A MODERATELY ABUNDANT HIGH MOBILITY GROUP-LIKE NUCLEAR-PROTEIN WITH AN ESSENTIAL FUNCTION IN SACCHAROMYCES-CEREVISIAE
    KOLODRUBETZ, D
    BURGUM, A
    [J]. YEAST, 1991, 7 (02) : 79 - 90
  • [9] ISOLATION AND ANALYSIS OF A HUMAN CDNA HIGHLY HOMOLOGOUS TO THE YEAST GENE ENCODING L17A RIBOSOMAL-PROTEIN
    BERCHTOLD, MW
    BERGER, MC
    [J]. GENE, 1991, 102 (02) : 283 - 288
  • [10] Novel pathological variants of NHP2 affect N-terminal domain flexibility, protein stability, H/ACA Ribonucleoprotein (RNP) complex formation and telomerase activity
    Malinski, Bartosz
    Vertemara, Jacopo
    Faustini, Elena
    Ladenvall, Claes
    Norberg, Anna
    Zhang, Yuming
    von Castelmur, Eleonore
    Baliakas, Panagiotis
    Tisi, Renata
    Cammenga, Jorg
    Lottersberger, Francisca
    [J]. HUMAN MOLECULAR GENETICS, 2023, 32 (19) : 2901 - 2912
12345