GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types

被引:18
|
作者
Sievers, Philipp [1 ,2 ]
Stichel, Damian [1 ,2 ]
Sill, Martin [3 ,4 ]
Schrimpf, Daniel [1 ,2 ]
Sturm, Dominik [3 ,5 ,25 ]
Selt, Florian [3 ,5 ,6 ]
Ecker, Jonas [3 ,5 ,6 ]
Kazdal, Daniel [7 ]
Miele, Evelina [8 ]
Kranendonk, Marieatte E. G. [9 ]
Tops, Bastiaan B. J. [9 ]
Kohlhof-Meinecke, Patricia [10 ]
Beschorner, Rudi [11 ]
Kramm, Christof M. [12 ]
Hasselblatt, Martin [13 ]
Reifenberger, Guido [14 ,15 ]
Capper, David [16 ,17 ,18 ,19 ]
Wesseling, Pieter [9 ,20 ,21 ]
Stenzinger, Albrecht [7 ]
Milde, Till [3 ,5 ,6 ]
Korshunov, Andrey [1 ,2 ,3 ]
Witt, Olaf [3 ,5 ,6 ]
Pfister, Stefan M. [3 ,4 ,5 ]
Wick, Wolfgang [22 ,23 ,24 ]
von Deimling, Andreas [1 ,2 ]
Jones, David T. W. [3 ,25 ]
Sahm, Felix [1 ,2 ,3 ]
机构
[1] Univ Hosp Heidelberg, Inst Pathol, Dept Neuropathol, Heidelberg, Germany
[2] German Canc Res Ctr, German Consortium Translat Canc Res DKTK, Clin Cooperat Unit Neuropathol, Heidelberg, Germany
[3] Hopp Childrens Canc Ctr Heidelberg KiTZ, Heidelberg, Germany
[4] German Canc Res Ctr, German Canc Consortium DKTK, Div Pediat Neurooncol, Heidelberg, Germany
[5] Univ Hosp Heidelberg, Dept Pediat Oncol Hematol Immunol & Pulmonol, Heidelberg, Germany
[6] German Canc Res Ctr, German Consortium Translat Canc Res DKTK, Clin Cooperat Unit Pediat Oncol, Heidelberg, Germany
[7] Univ Hosp Heidelberg, Inst Pathol, Heidelberg, Germany
[8] IRCCS Bambino Gesu Childrens Hosp, Dept Pediat Oncohematol & Cell & Gene Therapy, Rome, Italy
[9] Princess Maxima Ctr Pediat Oncol, Utrecht, Netherlands
[10] Klinikum Stuttgart, Dept Pathol, Stuttgart, Germany
[11] Univ Tubingen, Dept Neuropathol, Tubingen, Germany
[12] Univ Med Ctr Gottingen, Div Pediat Hematol & Oncol, Gottingen, Germany
[13] Univ Hosp Munster, Inst Neuropathol, Munster, Germany
[14] Heinrich Heine Univ, Inst Neuropathol, Dusseldorf, Germany
[15] German Canc Consortium DKTK, Partner Site Essen Dusseldorf, Dusseldorf, Germany
[16] Charite Univ Med Berlin, Berlin, Germany
[17] Free Univ Berlin, Berlin, Germany
[18] Humboldt Univ, Inst Neuropathol, Berlin, Germany
[19] German Canc Res Ctr, German Canc Consortium DKTK, Partner Site Berlin, Heidelberg, Germany
[20] Amsterdam Univ Med Ctr, Locat VUmc, Dept Pathol, Amsterdam, Netherlands
[21] Brain Tumor Ctr Amsterdam, Amsterdam, Netherlands
[22] German Canc Res Ctr, German Consortium Translat Canc Res DKTK, Clin Cooperat Unit Neurooncol, Heidelberg, Germany
[23] Heidelberg Univ Hosp, Natl Ctr Tumor Dis, Dept Neurol, Heidelberg, Germany
[24] Heidelberg Univ Hosp, Natl Ctr Tumor Dis, Neurooncol Program, Heidelberg, Germany
[25] German Canc Res Ctr, Pediat Glioma Res Grp, Heidelberg, Germany
关键词
CRIZOTINIB;
D O I
10.1007/s00401-021-02369-1
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
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页码:1065 / 1069
页数:5
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