The novel aminosterol antibiotics squalamine and 1436 are specific inhibitors of epithelial brush border Na+/H+ exchanger (NHE) isoform, NHE3.

被引：0
|
作者：
Nath, SK
Akhter, S
Tse, CM
Bowser, J
Williams, J
Zasloff, M
Donowitz, M
机构：
[1] JOHNS HOPKINS UNIV, SCH MED, DEPT MED, BALTIMORE, MD 21205 USA
[2] JOHNS HOPKINS UNIV, SCH MED, DEPT PHYSIOL, GI UNIT, BALTIMORE, MD 21205 USA
[3] MAGAININ PHARMACEUT, PLYMOUTH MEETIN, PA USA
来源：
GASTROENTEROLOGY | 1996年 / 110卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：A349 / A349
页数：1
相关论文
共 50 条
  • [21] The apical Na+/H+ exchanger isoform NHE3 is regulated by the actin cytoskeleton
    Kurashima, K
    D'Souza, S
    Szászi, K
    Ramjeesingh, R
    Orlowski, J
    Grinstein, S
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (42) : 29843 - 29849
  • [22] Transcriptional regulation of the human Na+/H+ exchanger NHE-3 isoform.
    Malakooti, J
    Memark, VC
    Dudeja, PK
    Ramaswamy, K
    GASTROENTEROLOGY, 2000, 118 (04) : A607 - A607
  • [23] NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin
    Yun, CHC
    Lamprecht, G
    Forster, DV
    Sider, A
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (40) : 25856 - 25863
  • [24] Role of the NHE(3) isoform of the Na+/H+ exchanger in sodium absorption by the rabbit gallbladder
    Silviani, V
    Colombani, V
    Heyries, L
    Gerolami, A
    Cartouzou, G
    Marteau, C
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1996, 432 (05): : 791 - 796
  • [25] LOCALIZATION OF THE NA+/H+ EXCHANGER ISOFORM NHE-3 IN RABBIT AND CANINE KIDNEY
    SOLEIMANI, M
    BOOKSTEIN, C
    BIZAL, GL
    MUSCH, MW
    HATTABAUGH, YJ
    RAO, MC
    CHANG, EB
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1994, 1195 (01): : 89 - 95
  • [26] cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein
    Yun, CHC
    Oh, S
    Zizak, M
    Steplock, D
    Tsao, S
    Tse, CM
    Weinman, EJ
    Donowitz, M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (07) : 3010 - 3015
  • [27] Na+/H+-exchanger 3 (NHE3) is present in lipid rafts in the ileal absorptive cell brush border:: A role for rafts and the actin cytoskeleton in endocytosis of NHE3.
    Li, XH
    Galli, T
    Louvard, D
    Donowitz, M
    GASTROENTEROLOGY, 2000, 118 (04) : A599 - A599
  • [28] Characterization of Na+/H+ exchanger isoform (NHE1, NHE2 and NHE3) expression in prairie dog gallbladder
    Abedin, MZ
    Giurgiu, DIN
    Abedin, ZR
    Peck, EA
    Su, X
    Smith, PR
    JOURNAL OF MEMBRANE BIOLOGY, 2001, 182 (02): : 123 - 134
  • [29] Characterization of Na+/H+ Exchanger Isoform (NHE1, NHE2 and NHE3) Expression in Prairie Dog Gallbladder
    M.Z. Abedin
    D.I.N. Giurgiu
    Z.R. Abedin
    E.A. Peck
    X. Su
    P.R. Smith
    The Journal of Membrane Biology, 2001, 182 : 123 - 134
  • [30] Immunolocalization of the Na+/H+ exchanger isoform NHE2 in rat kidney
    Chambrey, R
    Warnock, DG
    Podevin, RA
    Bruneval, P
    Mandet, C
    Bélair, MF
    Bariéty, J
    Paillard, M
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 1998, 275 (03) : F379 - F386
12345