The novel aminosterol antibiotics squalamine and 1436 are specific inhibitors of epithelial brush border Na+/H+ exchanger (NHE) isoform, NHE3.

被引：0
|
作者：
Nath, SK
Akhter, S
Tse, CM
Bowser, J
Williams, J
Zasloff, M
Donowitz, M
机构：
[1] JOHNS HOPKINS UNIV, SCH MED, DEPT MED, BALTIMORE, MD 21205 USA
[2] JOHNS HOPKINS UNIV, SCH MED, DEPT PHYSIOL, GI UNIT, BALTIMORE, MD 21205 USA
[3] MAGAININ PHARMACEUT, PLYMOUTH MEETIN, PA USA
来源：
GASTROENTEROLOGY | 1996年 / 110卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：A349 / A349
页数：1
相关论文
共 50 条
  • [1] Squalamine, a novel aminosterol antibiotic, is a specific inhibitor of epithelial brush border Na+/H+ exchanger isoform NHE3.
    Akhter, S
    Nath, SK
    Bowser, JM
    Tse, CM
    Williams, J
    Zasloff, M
    Donowitz, M
    FASEB JOURNAL, 1996, 10 (03): : 514 - 514
  • [2] HYPEROSMOLARITY INHIBITS THE EPITHELIAL SPECIFIC BRUSH-BORDER NA+,H+ EXCHANGER ISOFORM (NHE3)
    NATH, SK
    HANG, CY
    LEVINE, SA
    YUN, CH
    MONTROSE, MH
    DONOWITZ, M
    TSE, CM
    GASTROENTEROLOGY, 1994, 106 (04) : A258 - A258
  • [3] Squalamine, a novel cationic steroid, specifically inhibits the brush-border Na+/H+ exchanger isoform NHE3
    Akhter, S
    Nath, SK
    Tse, CM
    Williams, J
    Zasloff, M
    Donowitz, M
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1999, 276 (01): : C136 - C144
  • [4] NHE3 - A NA+/H+ EXCHANGER ISOFORM OF RENAL BRUSH-BORDER
    BIEMESDERFER, D
    PIZZONIA, J
    ABUALFA, A
    EXNER, M
    REILLY, R
    IGARASHI, P
    ARONSON, PS
    AMERICAN JOURNAL OF PHYSIOLOGY, 1993, 265 (05): : F736 - F742
  • [5] Tyrosine kinase is required for calmodulin to inhibit basal activity of the epithelial brush border Na+/H+ exchanger, NHE3.
    Nath, SK
    Akhter, S
    Levine, S
    Tse, CM
    Donowitz, M
    GASTROENTEROLOGY, 1996, 110 (04) : A349 - A349
  • [6] Proline rich regions of an epithelial NHE2 isoform of the Na+/H+ exchanger (NHE).
    Chow, CW
    Woodside, M
    Demaurex, N
    Rotin, D
    Yu, FH
    Orlowski, J
    Grinstein, S
    MOLECULAR BIOLOGY OF THE CELL, 1996, 7 : 1480 - 1480
  • [7] INITIAL CLONING OF THE HUMAN BRUSH-BORDER EPITHELIAL NA+/H+ EXCHANGER NHE3
    BRANT, SR
    YUN, CH
    DONOWITZ, M
    TSE, CM
    GASTROENTEROLOGY, 1994, 106 (04) : A225 - A225
  • [8] Human duodenal bicarbonate absorption involves both brush border Na+/H+ exchangers NHE2 and NHE3.
    Hogan, D
    Repishti, M
    Pratha, V
    Donowitz, M
    Tse, M
    Isenberg, J
    GASTROENTEROLOGY, 2000, 118 (04) : A606 - A606
  • [9] Glycosylation of the Na+/H+ exchanger isoform NHE-3 is species specific
    Bizal, GL
    Howard, RL
    Bookstein, C
    Rao, MC
    Chang, EB
    Soleimani, M
    JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1996, 128 (03): : 304 - 312
  • [10] GLUCOCORTICOID STIMULATION OF ILEAL NA+ ABSORPTIVE CELL BRUSH-BORDER NA+ H+ EXCHANGE AND ASSOCIATION WITH AN INCREASE IN MESSAGE FOR NHE-3, AN EPITHELIAL NA+ H+ EXCHANGER ISOFORM
    YUN, CHC
    GURUBHAGAVATULA, S
    LEVINE, SA
    MONTGOMERY, JLM
    BRANT, SR
    COHEN, ME
    CRAGOE, EJ
    POUYSSEGUR, J
    TSE, CM
    DONOWITZ, M
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (01) : 206 - 211
12345