Applicability of sheep and pig models for cancellous bone in human vertebral bodies

被引：3
|
作者：
Aslani, Farnaz Jabbary [1 ]
Hukins, David W. L. [1 ]
Shepherd, Duncan E. T. [1 ]
机构：
[1] Univ Birmingham, Sch Mech Engn, Birmingham, W Midlands, England
来源：
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE | 2012年 / 226卷 / H1期
关键词：
Animal models; bone mineral; spinal surgery; vertebrae; CORTICAL BONE; SEGMENTS;
D O I：
10.1177/0954411911426807
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The mineral content of cancellous bone from sheep and pig vertebral bodies was determined by ashing at 800 degrees C. The results were compared with published results for human vertebral cancellous bone. The results for sheep (0.37 +/- 0.06 g cm(-3), mean +/- standard deviation) were not significantly different (p=0.127) to those from pigs (0.33 +/- 0.03 g cm(-3)). The results from both species were significantly higher (p<0.001) than those from human bones (0.15 +/- 0.02 g cm(-3)). This means that cancellous bone from sheep and pig vertebral bodies is not a good model for corresponding human bone. However, sheep and pig bone are useful, for example, for providing stringent tests of cutting instruments to be used in human spinal surgery.
引用
收藏
页码：76 / 78
页数：3
相关论文
共 50 条
  • [41] Safety assessment of microwave ablation in sheep vertebral bodies
    Nijland, Hendricus
    Zhu, Jinwen
    Kwee, Thomas
    Hao, Ding-Jun
    Jutte, Paul
    INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2024, 41 (01)
  • [42] USE OF HUMAN LYOPHILIZED FIBRIN SEAL IN BONE PROSTHESIS OF CERVICAL VERTEBRAL BODIES
    LIGUORI, R
    DELGAIZO, S
    FUSCO, G
    DEBELLIS, M
    ACTA NEUROCHIRURGICA, 1983, 69 (1-2) : 152 - 152
  • [43] Mechanical failure begins preferentially near resorption cavities in human vertebral cancellous bone under compression
    Slyfield, C. R.
    Tkachenko, E. V.
    Fischer, S. E.
    Ehlert, K. M.
    Yi, I. H.
    Jekir, M. G.
    O'Brien, R. G.
    Keaveny, T. M.
    Hernandez, C. J.
    BONE, 2012, 50 (06) : 1281 - 1287
  • [44] Trabecular shear stress in human vertebral cancellous bone: intra- and inter-individual variations
    Yeni, YN
    Hou, FJ
    Vashishth, D
    Fyhrie, DP
    JOURNAL OF BIOMECHANICS, 2001, 34 (10) : 1341 - 1346
  • [45] Morphometric Comparison of the Lumbar Cancellous Bone of Sheep, Deer, and Humans
    Wang, Yang
    Liu, Guomin
    Li, Ting
    Xiao, Yanlong
    Han, Qing
    Xu, Randong
    Li, Youqiong
    COMPARATIVE MEDICINE, 2010, 60 (05) : 374 - 379
  • [46] A comparison of enhanced continuum FE with micro FE models of human vertebral bodies
    Pahr, Dieter H.
    Zysset, Philippe K.
    JOURNAL OF BIOMECHANICS, 2009, 42 (04) : 455 - 462
  • [47] Architecture of the cancellous bone of the human talus
    Pal, GP
    Routal, RV
    ANATOMICAL RECORD, 1998, 252 (02): : 185 - 193
  • [48] ZINC CONTENT OF HUMAN CANCELLOUS BONE
    ALHAVA, EM
    OLKKONEN, H
    PUITTINEN, J
    NOKSOKOIVISTO, VM
    ACTA ORTHOPAEDICA SCANDINAVICA, 1977, 48 (01): : 1 - 4
  • [49] Histomorphometric characterization of cancellous and cortical bone in an ovariectomized sheep model
    Giavaresi, G
    Fini, M
    Martini, L
    Aldini, NN
    Rocca, M
    Torricelli, P
    Giardino, R
    JOURNAL OF APPLIED ANIMAL RESEARCH, 2001, 20 (02) : 221 - 232
  • [50] ACOUSTICAL PROPERTIES OF HUMAN CANCELLOUS BONE
    SAHA, S
    SHAFKEY, R
    BIOMATERIALS MEDICAL DEVICES AND ARTIFICIAL ORGANS, 1986, 14 (1-2): : 79 - 79
12345