Applications of microbial proteases in pharmaceutical industry: an overview

被引：28
|
作者：
Chanalia, Preeti [1 ]
Gandhi, Dimpi [1 ]
Jodha, Drukshakshi [1 ]
Singh, Jasbir [1 ]
机构：
[1] Kurukshetra Univ, Dept Biochem, Kurukshetra 136119, Haryana, India
来源：
REVIEWS IN MEDICAL MICROBIOLOGY | 2011年 / 22卷 / 04期
关键词：
anti-inflammatory; industrial applications; pharmaceutical industry; proteases; PROTEOLYTIC-ENZYME SERRAPEPTASE; STAPHYLOCOCCUS-AUREUS; LYSOSTAPHIN TREATMENT; STREPTOKINASE; SERRATIOPEPTIDASE; ASPARAGINASE; BIOFILMS; KNEE; PAIN;
D O I：
10.1097/MRM.0b013e3283494749
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Proteases are ubiquitous to all the living organisms. Their involvement in the life cycle of various disease causing organisms has led them to become a potential target for developing therapeutic agents against life-threatening diseases such as bacterial infection, cancer, malaria and AIDS. This review is mainly focused on the applications of microbial proteases such as serrapeptase, serrazime, lysostaphin, L-asparaginase, L-glutaminase, streptokinase, streptokinase-streptodornase and xiaflex. These enzymes are being used in the treatment of inflammation, respiratory tract disorders, cardiovascular disease and cancer. (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins
引用
收藏
页码：96 / 101
页数：6
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