Management of Alcohol-Related Liver Disease and Its Complications

被引:5
|
作者
Cabezas, Joaquin [1 ]
机构
[1] Marques Valdecilla Univ Hosp, Clin & Translat Res Digest Dis Grp IDIVAL, Gastroenterol & Hepatol Dept, Santander, Cantabria, Spain
关键词
TRANSIENT ELASTOGRAPHY; LONG-TERM; HEPATITIS; FIBROSIS; ABSTINENCE; GUIDELINE; PROGNOSIS; CIRRHOSIS; BURDEN; TRENDS;
D O I
10.1007/s40261-022-01143-9
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Alcohol-related liver disease (ALD) is a major healthcare/economic burden and one of the leading causes of liver transplantation. New epidemiological studies that detail the course of the disease are needed since, despite its high prevalence, it is still a stigmatised condition with underlying pathology. Alcoholic hepatitis, as the highest expression of ALD, has high morbidity. Current treatments have suboptimal results with the exception of liver transplantation. Epidemiological studies must also be developed to improve prevention and implement early diagnosis policies. It is essential to develop multidisciplinary health models that allow the liver transplantation candidate to be approached in a holistic way, both for indication and follow up. The implementation of alcohol consumption biomarkers (ethyl glucuronide, phosphatidylethanol) can assist in diagnosing and supporting recovery. There are several initiatives with new therapies that must be validated to establish their effectiveness and indication.
引用
收藏
页码:47 / 53
页数:7
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