Schisandrin B Prevents Doxorubicin Induced Cardiac Dysfunction by Modulation of DNA Damage, Oxidative Stress and Inflammation Through Inhibition of MAPK/p53 Signaling

被引:1
|
作者
Konishi, Tetsuya [1 ]
Thandavarayan, Rajarajan A. [1 ]
Giridharan, Vijayasree V. [1 ]
Arunnugam, Somasundaram [1 ]
Watanabe, Kenichi [1 ]
机构
[1] Niigata Univ Pharm & Appl Life Sci, Niigata, Japan
关键词
D O I
10.1016/j.freeradbiomed.2011.10.133
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:S52 / S52
页数:1
相关论文
共 50 条
  • [21] Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: Role of NF-κB, p38 and JNK MAPK pathway
    Ghosh, Jyotirmoy
    Das, Joydeep
    Manna, Prasenjit
    Sil, Parames C.
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2009, 240 (01) : 73 - 87
  • [22] Selenium attenuates lipopolysaccharide-induced oxidative stress responses through modulation of p38 MAPK and NF-κB signaling pathways
    Kim, SH
    Johnson, VJ
    Shin, TY
    Sharma, RP
    EXPERIMENTAL BIOLOGY AND MEDICINE, 2004, 229 (02) : 203 - 213
  • [23] Schisandrin B inhibits inflammation and ferroptosis in S.aureus-induced mastitis through regulating SIRT1/p53/SLC7A11 signaling pathway
    Zhou, Di
    Sun, Liang
    Li, Jun
    Yang, Yang
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 137
  • [24] YTHDF2 Regulates Macrophage Polarization through NF-κB and MAPK Signaling Pathway Inhibition or p53 Degradation
    Cai, Luhui
    Li, Di
    Feng, Zhihui
    Gu, Xiaofei
    Xu, Qiong
    Li, Qimeng
    DISEASE MARKERS, 2022, 2022
  • [25] p53 Regulates Oxidative Stress-Mediated Retrograde Signaling: A Novel Mechanism for Chemotherapy-Induced Cardiac Injury
    Velez, Joyce M.
    Miriyala, Sumitra
    Nithipongvanitch, Ramaneeya
    Noel, Teresa
    Plabplueng, Chotiros D.
    Oberley, Terry
    Jungsuwadee, Paiboon
    Van Remmen, Holly
    Vore, Mary
    Clair, Daret K. St.
    PLOS ONE, 2011, 6 (03):
  • [26] Complex p53 dynamics regulated by miR-125b in cellular responses to reactive oxidative stress and DNA damage
    Malik, Md Zubbair
    Dashti, Mohammed
    Jangid, Amit
    Channanath, Arshad
    John, Sumi Elsa
    Singh, R. K. Brojen
    Al-Mulla, Fahd
    Thanaraj, Thangavel Alphonse
    BRIEFINGS IN BIOINFORMATICS, 2025, 26 (01)
  • [27] Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats
    Imam, Faisal
    Al-Harbi, Naif O.
    Al-Harbi, Mohammad Matar
    Ansari, Mushtaq Ahmad
    Almutairi, Mashal M.
    Alshammari, Musaad
    Almukhlafi, Talal Saad
    Ansari, Mohd Nazam
    Aljerian, Khaldoon
    Ahmad, Sheikh Fayaz
    TOXICOLOGY MECHANISMS AND METHODS, 2016, 26 (09) : 700 - 708
  • [28] Phorate-induced oxidative stress, DNA damage and transcriptional activation of p53 and caspase genes in male Wistar rats
    Saquib, Quaiser
    Attia, Sabry M.
    Siddiqui, Maqsood A.
    Aboul-Soud, Mourad A. M.
    Al-Khedhairy, Abdulaziz A.
    Giesy, John P.
    Musarrat, Javed
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 259 (01) : 54 - 65
  • [29] IGF-1 Prevents Oxidative Stress Induced-Mitochondria Dysfunction and Cell Cycle Arrest in Human Cardiac Progenitor Cells via P53/PGC Pathway
    Li, Yangxin
    Shelat, Harnath
    Gao, Song
    Geng, Yong-Jian
    CIRCULATION, 2012, 126 (21)
  • [30] Lactobacillus brevis 23017 Relieves Mercury Toxicity in the Colon by Modulation of Oxidative Stress and Inflammation Through the Interplay of MAPK and NF-κB Signaling Cascades
    Jiang, Xinpeng
    Gu, Shanshan
    Liu, Di
    Zhao, Lili
    Xia, Shuang
    He, Xinmiao
    Chen, Hongyan
    Ge, Junwei
    FRONTIERS IN MICROBIOLOGY, 2018, 9