Insights into CD4+ memory T cells following Leishmania infection

被引:21
|
作者
Gollob, KJ [1 ]
Antonelli, LRV
Dutra, WO
机构
[1] Univ Fed Minas Gerais, Inst Biol Sci, Dept Biochem & Immunol, BR-30161970 Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais, Inst Biol Sci, Dept Morphol, BR-30161970 Belo Horizonte, MG, Brazil
关键词
D O I
10.1016/j.pt.2005.06.007
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Recent publications by Zaph et al. have highlighted the distinct requirements for generating and maintaining different subpopulations of CD4(+) memory T cells after infection with Leishmania major in mice. These studies have advanced the understanding of the nature of long-lasting immunity to Leishmania and, when considered within the context of previous work on both murine and human leishmaniasis, will aid the design of effective vaccines.
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页码:347 / 350
页数:4
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