Bioactive Oleic Derivatives of Dopamine: A Review of the Therapeutic Potential

被引:2
|
作者
Pokorski, Mieczyslaw [1 ]
Zajac, Dominika [2 ]
机构
[1] Opole Med Sch, Fac Physiotherapy, Opole, Poland
[2] Mossakowski Med Res Ctr PAS, Lab Respirat Physiol, Warsaw, Poland
来源
关键词
Brain; Dopamine receptor; Lipid derivatives of dopamine; Therapeutic potential; TRPV1; receptors; N-OLEOYL-DOPAMINE; TRPV1; RECEPTORS; ACYL-DOPAMINES; IN-VITRO; CAPSAICIN; OLEOYLDOPAMINE; INHIBITORS; ACTIVATION; INVOLVEMENT; NEURONS;
D O I
10.1007/5584_2018_197
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Lipid derivatives of dopamine are a novel class of compounds raising a research interest due to the potential of their being a vehicle for dopamine delivery to the brain. The aim of the present paper is to review the main features of the two most prominent bioactive members of this family, namely, N-oleoyl-dopamine (OLDA) and 3'-O-methyl-N-oleoyl-dopamine (OMe-OLDA), with emphasis on the possible therapeutic properties.
引用
收藏
页码:73 / 82
页数:10
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