Vertical Transmission and Neonatal Outcomes Following Maternal SARS-CoV-2 Infection During Pregnancy

被引：21
|
作者：
Kyle, Margaret H. [1 ]
Hussain, Maha [1 ]
Saltz, Victoria [4 ]
Mollicone, Isabelle [1 ]
Bence, Mary [1 ]
Dumitriu, Dani [1 ,2 ,3 ]
机构：
[1] Columbia Univ, Dept Pediat, Irving Med Ctr, New York, NY 10027 USA
[2] Columbia Univ, Dept Psychiat, Irving Med Ctr, New York, NY USA
[3] Columbia Univ, Irving Med Ctr, Nurture Sci Program, New York, NY USA
[4] Williams Coll, Dept Psychol, Williamstown, MA 01267 USA
来源：
CLINICAL OBSTETRICS AND GYNECOLOGY | 2022年 / 65卷 / 01期
基金：
美国国家卫生研究院;
关键词：
SARS-CoV-2; COVID-19; neonatal; pregnancy; vertical transmission; breastfeeding;
D O I：
10.1097/GRF.0000000000000667
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 200 million people worldwide and has likely exposed millions of neonates to SARS-CoV-2 in utero. A large body of literature has examined the possibility of vertical transmission from pregnant women infected with SARS-CoV-2 to their neonates. In this chapter, we review mechanisms of-and evidence for-vertical transmission of SARS-CoV-2, including transplacental, through other biospecimens and breastfeeding, and discuss neonatal outcomes following in utero exposure. Based on the available literature, we conclude vertical transmission of SARS-CoV-2 is rare, and exposed neonates generally show favorable health outcomes.
引用
收藏
页码：195 / 202
页数：8
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