Vertical Transmission and Neonatal Outcomes Following Maternal SARS-CoV-2 Infection During Pregnancy

被引：21

作者：

Kyle, Margaret H. ^{[1
]}

Hussain, Maha ^{[1
]}

Saltz, Victoria ^{[4
]}

Mollicone, Isabelle ^{[1
]}

Bence, Mary ^{[1
]}

Dumitriu, Dani ^{[1
,2
,3
]}

机构：

[1] Columbia Univ, Dept Pediat, Irving Med Ctr, New York, NY 10027 USA

[2] Columbia Univ, Dept Psychiat, Irving Med Ctr, New York, NY USA

[3] Columbia Univ, Irving Med Ctr, Nurture Sci Program, New York, NY USA

[4] Williams Coll, Dept Psychol, Williamstown, MA 01267 USA

来源：

CLINICAL OBSTETRICS AND GYNECOLOGY | 2022年 / 65卷 / 01期

基金：

美国国家卫生研究院;

关键词：

SARS-CoV-2; COVID-19; neonatal; pregnancy; vertical transmission; breastfeeding;

D O I：

10.1097/GRF.0000000000000667

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 200 million people worldwide and has likely exposed millions of neonates to SARS-CoV-2 in utero. A large body of literature has examined the possibility of vertical transmission from pregnant women infected with SARS-CoV-2 to their neonates. In this chapter, we review mechanisms of-and evidence for-vertical transmission of SARS-CoV-2, including transplacental, through other biospecimens and breastfeeding, and discuss neonatal outcomes following in utero exposure. Based on the available literature, we conclude vertical transmission of SARS-CoV-2 is rare, and exposed neonates generally show favorable health outcomes.

引用

页码：195 / 202

页数：8

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