SYNTHESIS AND ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF THIOUREA DERIVATIVES OF THE ALKALOID ANABASINE

被引：29

作者：

Kulakov, I. V. ^{[1
]}

Nurkenov, O. A. ^{[1
]}

Akhmetova, S. B. ^{[2
]}

Seidakhmetova, R. B. ^{[2
]}

Zhambekov, Z. M.

机构：

[1] Republ Kazakhstan Inst Organ Synth & Carbochem, Karaganda, Kazakhstan

[2] Fitokhimiya Sci & Prod Ctr, Karaganda, Kazakhstan

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2011年 / 45卷 / 01期

关键词：

Anabasine; antibacterial and antifungal activities; BRINE SHRIMP;

D O I：

10.1007/s11094-011-0551-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of new N-acyl-substituted derivatives of the physiologically active alkaloid anabasine were synthesized and described. Their compositions and structures were identified using IR and (1)H NMR spectroscopy. These compounds were found to have moderate antibacterial and antifungal activities.

引用

页码：15 / 18

页数：4

共 50 条

[1] Synthesis and antibacterial and antifungal activities of thiourea derivatives of the alkaloid anabasine
I. V. Kulakov
O. A. Nurkenov
S. B. Akhmetova
R. B. Seidakhmetova
Z. M. Zhambekov
[J]. Pharmaceutical Chemistry Journal, 2011, 45 : 15 - 18
[2] Synthesis and antibacterial properties of some derivatives of alkaloid anabasine
Fazylov, S. D.
Nurkenov, O. A.
Tazhbayev, E. M.
Kulakov, I. V.
Zhivotova, T. S.
Kazhmuratova, A. T.
Satpayeva, Zh. B.
[J]. BULLETIN OF THE UNIVERSITY OF KARAGANDA-CHEMISTRY, 2012, (68): : 24 - 28
[3] Thiourea derivatives incorporating a hippuric acid moiety: Synthesis and evaluation of antibacterial and antifungal activities
Abbas, Samir Y.
El-Sharief, Marwa A. M. Sh.
Basyouni, Wahid M.
Fakhr, Issa M. I.
El-Gammal, Eman W.
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 64 : 111 - 120
[4] Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities
Yavuz, Serkan
Yjldjrjm, Hilal
[J]. JOURNAL OF CHEMISTRY, 2013, 2013
[5] Synthesis of benzimidazole derivatives and their antibacterial and antifungal activities
Bhatt, AK
Karadiya, H
Shah, PR
Parmar, MP
Patel, HD
[J]. INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2003, 13 (02) : 187 - 188
[6] Synthesis, Antibacterial and Antifungal Activities of Bifonazole Derivatives
El Hage, Salome
Lajoie, Barbora
Feuillolay, Catherine
Roques, Christine
Baziard, Genevieve
[J]. ARCHIV DER PHARMAZIE, 2011, 344 (06) : 402 - 410
[7] Synthesis, antibacterial, and antifungal activities of new pyrimidinone derivatives
Cherif, Oussama
Masmoudi, Fatma
Allouche, Fatma
Chabchoub, Fakher
Trigui, Mohamed
[J]. HETEROCYCLIC COMMUNICATIONS, 2015, 21 (04) : 191 - 194
[8] Synthesis of some benzimidazole derivatives and their antibacterial and antifungal activities
Küçükbay, H
Durmaz, R
Güven, M
Günal, S
[J]. ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 2001, 51 (05): : 420 - 424
[9] Synthesis and in vitro Antibacterial and Antifungal Activities of Benzoxazole Derivatives
Khan, Khalid Mohammed
Karim, Aneela
Ambreen, Nida
Amyn, Afroz
Saied, Sumayya
Ahmed, Aqeel
Perveen, Shahnaz
[J]. JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 2013, 35 (03): : 894 - 900
[10] Synthesis, antibacterial and antifungal activities of some carbazole derivatives
Zhang, Fei-Fei
Gan, Lin-Ling
Zhou, Cheng-He
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (06) : 1881 - 1884

← 1 2 3 4 5 →