Conjunctival Impression Cytology and Dry Eye in Patients With Ulcerative Colitis: A Pilot Study

被引：9
|
作者：
Oltulu, Pembe [1 ]
Oltulu, Refik [2 ]
Asil, Mehmet [3 ]
Satirtav, Gunhal [2 ]
Mirza, Enver [2 ]
机构：
[1] Necmettin Erbakan Univ, Meram Fac Med, Dept Pathol, Konya, Turkey
[2] Necmettin Erbakan Univ, Meram Fac Med, Dept Ophthalmol, TR-42080 Konya, Turkey
[3] Necmettin Erbakan Univ, Meram Fac Med, Dept Gastroenterol, Konya, Turkey
来源：
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE | 2018年 / 44卷
关键词：
Ulcerative colitis; Dry eye; Conjunctival impression cytology; INFLAMMATORY-BOWEL-DISEASE; RISK-FACTORS; MANIFESTATIONS; FREQUENCY;
D O I：
10.1097/ICL.0000000000000380
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: The aim of this study was to compare signs of dry eye between ulcerative colitis (UC) patients and healthy subjects. Methods: Fifteen patients with UC (group 1) and 15 healthy subjects (group 2) were enrolled in this study. Tear volume measurement, Schirmer-I test with no anesthetic, tear break-up time, and conjunctival impression cytology (CIC) were evaluated in both groups. Results: Patients with UC showed lower tear volumes when compared with healthy subjects (P<0.05). There was a statistically significant difference in distribution of CIC grades between groups 1 and 2 (P<0.05). Tear break-up time and Schirmer-I measurements were significantly lower in group 1 compared with group 2 (P<0.05). Conclusions: The results of this study indicate that UC is associated with demonstrable disturbances in tear function and conjunctival cytology.
引用
收藏
页码：S190 / S193
页数：4
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