No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis

被引：1
|
作者：
Claude, F. [1 ]
Rochat, I. [2 ]
Hafen, G. M. [2 ]
机构：
[1] Univ Lausanne, Fac Biol & Med, Lausanne, Switzerland
[2] CHU Vaudois, Dept Pediat, Resp Unit, Lausanne, Switzerland
来源：
BMC RESEARCH NOTES | 2019年 / 12卷 / 1期
关键词：
Cystic fibrosis; Eradication protocol; Primoinfection; Pseudomonas aeruginosa;
D O I：
10.1186/s13104-019-4157-8
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Objective: Patients with cystic fibrosis are more susceptible than members of the general population to lung infections. Infections with Pseudomonas aeruginosa require particular attention, because they may accelerate the deterioration of lung function if not adequately treated. This study assessed the eradication rate of P. aeruginosa primoinfections, with a protocol of inhaled tobramycin and oral ciprofloxacin over a 3 months' period. Results: Retrospective single-center study from June 1st, 2007 to December 31st, 2015. Inclusion of 28 pediatric patients (11 females, 17 males), with a total of 49 primoinfections. Overall success rate of 67.3%, which is similar or even inferior to figures published in the literature.
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页数：6
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