COX-2 selective inhibitors and heart health

被引：0
|
作者：
Simon, Lee S. [3 ,4 ]
White, William B. [1 ,2 ]
机构：
[1] Univ Connecticut, Ctr Hlth, Clin Trials Unit, Farmington, CT 06030 USA
[2] Univ Connecticut, Sch Med, Calhoun Cardiol Ctr, Farmington, CT 06030 USA
[3] Harvard Univ, Sch Med, Boston, MA USA
[4] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
来源：
POSTGRADUATE MEDICINE | 2005年
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
On September 30, 2004, because of an observed increased risk of serious cardiovascular (CV) events, Merck & Co, Inc, voluntarily withdrew rofecoxib from the worldwide market. The withdrawal has focused attention on the possible class effect on the cardiovascular system of the other currently available cyclooxygenase-2 (COX-2) selective inhibitors: celecoxib and valdecoxib. This review evaluates and differentiates the CV effects of COX-2 selective inhibitors through an assessment of prospective, randomized epidemiologic studies and meta-analyses.
引用
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页码：7 / 20
页数：14
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