Novel (2R,3R)-2,3-Butanediol Dehydrogenase from Potential Industrial Strain Paenibacillus polymyxa ATCC 12321

被引:67
|
作者
Yu, Bo [1 ]
Sun, Jibin [1 ,2 ]
Bommareddy, Rajesh Reddy [1 ]
Song, Lifu [1 ,2 ]
Zeng, An-Ping [1 ]
机构
[1] Hamburg Univ Technol, Inst Bioproc & Biosyst Engn, D-21071 Hamburg, Germany
[2] Chinese Acad Sci, Key Lab Syst Microbial Biotechnol, Tianjin Inst Ind Biotechnol, Tianjin 300308, Peoples R China
关键词
GENOME SEQUENCE; GENE; RHIZOBACTERIUM; EXPRESSION; CLONING; MDR; SDR;
D O I
10.1128/AEM.02998-10
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A (2R,3R)-2,3-butanediol dehydrogenase (BDH99::67) from Paenibacillus polymyxa ATCC 12321 was functionally characterized. The genetic characteristics of BDH99:: 67 are completely different from those of meso- and (2S,3S)-2,3-butanediol dehydrogenases. The results showed that BDH99:: 67 belongs to the medium-chain dehydrogenase/reductase superfamily and not to the short-chain dehydrogenase/reductase superfamily, to which meso-and (2S, 3S)-2,3-butanediol dehydrogenases belong.
引用
收藏
页码:4230 / 4233
页数:4
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